πŸ›οΈ Verified NIH Record β€’ Updated 2026-07-24

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1) (NCT06959225)

A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa

πŸ”΅ Active, Not Recruiting Phase3 πŸ’Š Investigational Drug / Biologic Sponsor: Incyte Corporation

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.

Who can join: Review the eligibility criteria below.

Location: Investigative Site US020 β€” Phoenix, Arizona

Age range: 12 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (101 Sites)

Showing the first 25 of 101 sites.

  • Investigative Site US020 β€” Phoenix, Arizona
  • Investigative Site US033 β€” Scottsdale, Arizona
  • Investigative Site US054 β€” Tempe, Arizona
  • Investigative Site US002 β€” Fayetteville, Arkansas
  • Investigative Site US055 β€” Brea, California
  • Investigative Site US004 β€” Laguna Niguel, California
  • Investigative Site US007 β€” Los Angeles, California
  • Investigative Site US013 β€” San Diego, California
  • Investigative Site US060 β€” San Diego, California
  • Investigative Site US038 β€” San Diego, California
  • Investigative Site US059 β€” Aurora, Colorado
  • Investigative Site US045 β€” Boynton Beach, Florida
  • Investigative Site US028 β€” Fort Myers, Florida
  • Investigative Site US016 β€” Miami, Florida
  • Investigative Site US027 β€” Sanford, Florida
  • Investigative Site US057 β€” Sweetwater, Florida
  • Investigative Site US029 β€” Tampa, Florida
  • Investigative Site US061 β€” Atlanta, Georgia
  • Investigative Site US053 β€” Atlanta, Georgia
  • Investigative Site US019 β€” Marietta, Georgia
  • Investigative Site US026 β€” Chicago, Illinois
  • Investigative Site US049 β€” Clarksville, Indiana
  • Investigative Site US052 β€” West Lafayette, Indiana
  • Investigative Site US001 β€” Bowling Green, Kentucky
  • Investigative Site US022 β€” Louisville, Kentucky

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—