ποΈ Verified NIH Record β’ Updated 2026-07-24
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1) (NCT06959225)
A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic Sponsor: Incyte Corporation
π©Ί Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.
Who can join: Review the eligibility criteria below.
Location: Investigative Site US020 β Phoenix, Arizona
Age range: 12 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (101 Sites)
Showing the first 25 of 101 sites.
- Investigative Site US020 β Phoenix, Arizona
- Investigative Site US033 β Scottsdale, Arizona
- Investigative Site US054 β Tempe, Arizona
- Investigative Site US002 β Fayetteville, Arkansas
- Investigative Site US055 β Brea, California
- Investigative Site US004 β Laguna Niguel, California
- Investigative Site US007 β Los Angeles, California
- Investigative Site US013 β San Diego, California
- Investigative Site US060 β San Diego, California
- Investigative Site US038 β San Diego, California
- Investigative Site US059 β Aurora, Colorado
- Investigative Site US045 β Boynton Beach, Florida
- Investigative Site US028 β Fort Myers, Florida
- Investigative Site US016 β Miami, Florida
- Investigative Site US027 β Sanford, Florida
- Investigative Site US057 β Sweetwater, Florida
- Investigative Site US029 β Tampa, Florida
- Investigative Site US061 β Atlanta, Georgia
- Investigative Site US053 β Atlanta, Georgia
- Investigative Site US019 β Marietta, Georgia
- Investigative Site US026 β Chicago, Illinois
- Investigative Site US049 β Clarksville, Indiana
- Investigative Site US052 β West Lafayette, Indiana
- Investigative Site US001 β Bowling Green, Kentucky
- Investigative Site US022 β Louisville, Kentucky
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hidradenitis Suppurativa
- A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are NaΓ―ve to Biologic Therapy β Phoenix, Arizona
- Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa β Boston, Massachusetts
- A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa β Phoenix, Arizona
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2) β Birmingham, Alabama
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa β Birmingham, Alabama
Explore by condition: All Hidradenitis Suppurativa clinical trials
π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.