A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma (NCT06977581)
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-group, Dose-Ranging Study to Investigate the Efficacy and Safety of PF-07275315 in Adult Participants With Inadequately Controlled Moderate-to-Severe Asthma
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected. This study is seeking participants who: * Are 18 to 70 years old * Have had moderate-to-severe asthma for at least 12 months that is not well controlled * Have been taking their regular maintenance treatment(s) for asthma over the last 12 months All participants will receive PF-07275315 or a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. PF-07275315 or placebo will be given as multiple shots in the clinic over the course of 12 weeks. We will compare the experiences of people receiving PF-07275315 to those of the people who do not. This will help us determine if PF-07275315 is safe and effective. Participants will be involved in this study for about 7.5 months. During this time, they will have 9 visits at the study clinic.
Who can join: Review the eligibility criteria below.
Location: Velocity Clinical Research, Mobile — Mobile, Alabama
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (132 Sites)
Showing the first 25 of 132 sites.
- Velocity Clinical Research, Mobile — Mobile, Alabama
- Chandler Clinical Trials — Chandler, Arizona
- Antelope Valley Clinical Trials — Lancaster, California
- NewportNativeMD, Inc. — Newport Beach, California
- California Medical Research Associates — Northridge, California
- Allergy and Asthma Associates of Santa Clara Valley Research Center — San Jose, California
- Allergy & Asthma Clinical Research — Walnut Creek, California
- Colorado ENT & Allergy — Colorado Springs, Colorado
- Cpcc-Research Llc — East Point, Georgia
- Christie Clinic - University — Champaign, Illinois
- Innovo Research - Christie Clinic — Champaign, Illinois
- Christie Clinic - Windsor — Champaign, Illinois
- University of Kansas Medical Center — Kansas City, Kansas
- North Ingalls Building — Ann Arbor, Michigan
- University of Michigan — Ann Arbor, Michigan
- Washington University School of Medicine — St Louis, Missouri
- Henderson Clinical Trials — Henderson, Nevada
- Rutgers, Robert Wood Johnson Medical School — New Brunswick, New Jersey
- Circuit Clinical / Impact Medical Allergy, Asthma & Immunology — Riverdale, New Jersey
- American Health Research — Charlotte, North Carolina
- Clinical Research Of Gastonia — Gastonia, North Carolina
- Stern Research Partners, LLC — Huntersville, North Carolina
- Toledo Institute of Clinical Research Inc. — Toledo, Ohio
- OK Clinical Research — Edmond, Oklahoma
- Allergy, Asthma and Clinical Research — Oklahoma City, Oklahoma
📞 Contact the Study Coordinator
Phone: (800) 718-1021
Email: ClinicalTrials.gov_Inquiries@pfizer.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Asthma
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- Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma — Bakersfield, California
- Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma — Saraland, Alabama
- Reduce IDentified UNcontrolled Asthma — San Diego, California
- A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma — Little Rock, Arkansas
- REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study — La Jolla, California
Explore by condition: All Asthma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.