A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer (NCT06992258)

🧪 Interventions in This Study

• Fruquintinib+ Lonsurf (trifluridine and tipiracil) (DRUG)
• Fruquintinib (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (9 Sites)

• Yale University — New Haven, Connecticut
• Mount Sinai Cancer Research Program — Miami Beach, Florida
• Orlando Health Cancer Institute — Orlando, Florida
• Rutgers Cancer Institute — New Brunswick, New Jersey
• NYU Langone Health — New York, New York
• UPenn Lancaster-Ann B. Barshinger Cancer Institute — Lancaster, Pennsylvania
• Vanderbilt University Medical Center — Nashville, Tennessee
• Mays Cancer Center at University of Texas Health at San Antonio — San Antonio, Texas
• Inova Schar Cancer — Fairfax, Virginia

📞 Contact the Study Coordinator

Phone: (518) 828-1274

Email: FRUQ004PM@criteriuminc.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.