๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-11

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension (NCT06992440)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Gustavo A Heresi, MD, MS

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Randomized, triple-masked, parallel arm clinical trial of empagliflozin versus placebo in pulmonary arterial hypertension (PAH) participants on stable approved PAH-targeted medical therapy.

Who can join: Review the eligibility criteria below.

Location: The Johns Hopkins Hospital โ€” Baltimore, Maryland

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (3 Sites)

  • The Johns Hopkins Hospital โ€” Baltimore, Maryland
  • Cleveland Clinic โ€” Cleveland, Ohio
  • Vanderbilt University Medical Center โ€” Nashville, Tennessee

๐Ÿ“ž Contact the Study Coordinator

Phone: (216) 636-5327

Email: HERESIG@ccf.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—