๐๏ธ Verified NIH Record โข Updated 2026-08-11
Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension (NCT06992440)
๐ข Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Gustavo A Heresi, MD, MS
๐ฉบ Plain-English Summary (8th-Grade Level)
Randomized, triple-masked, parallel arm clinical trial of empagliflozin versus placebo in pulmonary arterial hypertension (PAH) participants on stable approved PAH-targeted medical therapy.
Who can join: Review the eligibility criteria below.
Location: The Johns Hopkins Hospital โ Baltimore, Maryland
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (3 Sites)
- The Johns Hopkins Hospital โ Baltimore, Maryland
- Cleveland Clinic โ Cleveland, Ohio
- Vanderbilt University Medical Center โ Nashville, Tennessee
๐ Contact the Study Coordinator
Phone: (216) 636-5327
Email: HERESIG@ccf.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Pulmonary Arterial Hypertension
- A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION) โ Aurora, Colorado
- A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension โ Phoenix, Arizona
- Pulmonary Vascular Disease Phenomics Program PVDOMICS โ Tucson, Arizona
- An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) โ Jacksonville, Florida
- A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension โ Aurora, Colorado
- ADAPT - A Patient Registry of the Real-world Use of Orenitramยฎ โ Fresno, California
Explore by condition: All Pulmonary Arterial Hypertension clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.