A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised (NCT07013474)
AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 3, RANDOMIZED, DOUBLE-BLIND, 3-ARM STUDY TO INVESTIGATE IBUZATRELVIR IN ADULTS WITH SYMPTOMATIC COVID-19 WHO ARE SEVERELY IMMUNOCOMPROMISED
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase 3, randomized, actively controlled, double-blinded, double-dummy, superiority study to evaluate the efficacy and safety of ibuzatrelvir alone and in combination with remdesivir IV compared to remdesivir IV alone for the treatment of symptomatic COVID-19 in severely immunocompromised adult participants who are non-hospitalized or are hospitalized at baseline with mild-to-moderate COVID-19.
Who can join: Review the eligibility criteria below.
Location: Hope Clinical Research, Inc. — Canoga Park, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (152 Sites)
Showing the first 25 of 152 sites.
- Hope Clinical Research, Inc. — Canoga Park, California
- Amicis Research Center - Granada Hills — Granada Hills, California
- Jacobs Medical Center at UC San Diego Health — La Jolla, California
- UC Davis CTSC Clinical Research Center — Sacramento, California
- University of California Davis Health — Sacramento, California
- UC San Diego Medical Center - Hillcrest — San Diego, California
- University of California San Diego Health — San Diego, California
- UCHealth Anschutz Inpatient Pavilion - Anschutz Medical Campus — Aurora, Colorado
- University of Colorado Anschutz Medical Campus — Aurora, Colorado
- University of Colorado Clinical and Translational Research Center — Aurora, Colorado
- University of Colorado Hospital — Aurora, Colorado
- Georgetown University Medical Center — Washington D.C., District of Columbia
- BRP- Hialeah Hospital — Hialeah, Florida
- D&H Cancer Research Center LLC — Margate, Florida
- Kendall South Medical Center — Miami, Florida
- Velocity Clinical Research, Savannah — Savannah, Georgia
- Humphreys Diabetes Center — Boise, Idaho
- St. Luke's Idaho Elks Children's Pavilion — Boise, Idaho
- Northwestern Memorial Hospital — Chicago, Illinois
- Northwestern University Feinberg School of Medicine — Chicago, Illinois
- Johns Hopkins Hospital — Baltimore, Maryland
- Jadestone Clinical Research — Silver Spring, Maryland
- Brigham and Women's Hospital — Boston, Massachusetts
- Clinical Trials Center — Boston, Massachusetts
- Clinical Trials Hub — Boston, Massachusetts
📞 Contact the Study Coordinator
Phone: (800) 718-1021
Email: ClinicalTrials.gov_Inquiries@pfizer.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.