A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma (NCT07015242)
The CAROLYN Trial: Lisocabtagene Maraleucel as First-Line Therapy for Primary Central Nervous System Lymphoma (PCNSL) in Transplant-Ineligible Patients
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the safety and efficacy of lisocabtagene maraleucel (Breyanzi/liso-cel/BMS-986387) in adults as first-line treatment in transplant-ineligible Primary Central Nervous System Lymphoma (PCNSL).
Who can join: Review the eligibility criteria below.
Location: University Of Colorado — Aurora, Colorado
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (40 Sites)
Showing the first 25 of 40 sites.
- University Of Colorado — Aurora, Colorado
- Moffitt Cancer Center — Tampa, Florida
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University — Chicago, Illinois
- Dana-Farber Cancer Institute — Boston, Massachusetts
- Washington University School of Medicine in St. Louis — St Louis, Missouri
- Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey
- Roswell Park Comprehensive Cancer Center — Buffalo, New York
- Memorial Sloan Kettering Cancer Center — New York, New York
- Cleveland Clinic — Cleveland, Ohio
- The Ohio State University Comprehensive Cancer Center — Columbus, Ohio
- University of Pennsylvania — Philadelphia, Pennsylvania
- Sarah Cannon Research Institute Oncology Partners — Nashville, Tennessee
- MD Anderson Cancer Center — Houston, Texas
- Fred Hutchinson Cancer Center — Seattle, Washington
- Local Institution - 0111 — Nice, Alpes-Maritimes
- Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu — Nantes, Loire-Atlantique
- Local Institution - 0103 — Pierre-Bénite, Rhône
- CHU de Dijon Bourgogne - Hopital Francois Mitterand — Dijon,
- Chru De Lille - Hopital Claude Huriez — Lille,
- Local Institution - 0112 — Marseille,
- CHU Montpellier — Montpellier,
- Local Institution - 0114 — Paris,
- Local Institution - 0102 — Paris,
- Local Institution - 0108 — Pessac,
- CHU de Rennes - Hopital de Pontchaillou — Rennes,
📞 Contact the Study Coordinator
Phone: (855) 907-3286
Email: Clinical.Trials@bms.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.