Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity (NCT07037433)
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
🩺 Plain-English Summary (8th-Grade Level)
The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of care with respect to reducing cardiovascular (CV) morbidity and mortality.
Who can join: Review the eligibility criteria below.
Location: Alliance For Multispecialty Research - Daphne — Daphne, Alabama
Age range: 45 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (782 Sites)
Showing the first 25 of 782 sites.
- Alliance For Multispecialty Research - Daphne — Daphne, Alabama
- Eastern Shore Research Institute — Fairhope, Alabama
- Heart Center Research LLC — Huntsville, Alabama
- Mobile Heart Specialists PC — Mobile, Alabama
- Syed Research Consultants LLC — Sheffield, Alabama
- Synexus Clinical Research US, Inc. — Phoenix, Arizona
- Medical Advancement Centers of Arizona — Phoenix, Arizona
- Valley Clinical Trials, LLC dba Flourish Research — Covina, California
- Velocity Clinical Research- Huntington Park — Huntington Park, California
- Velocity Clinical Research- Los Angeles — La Mesa, California
- Orange County Research Center — Lake Forest, California
- Biopharma Informatic - The Cardiovascular Center — Redding, California
- Acclaim Clinical Research — San Diego, California
- Encompass Clinical Research — Spring Valley, California
- Diablo Clinical Research — Walnut Creek, California
- Focus Clinical Research — West Hills, California
- Family Practice Associates — Wilmington, Delaware
- Excel Medical Clinical Trials — Boca Raton, Florida
- Velocity Clinical Research - New Smyrna Beach — Edgewater, Florida
- Alliance for Multispecialty Research - Fort Myers — Fort Myers, Florida
- Elite Cardiac Research Center LLC — Hialeah, Florida
- Elite Clinical Research — Hialeah, Florida
- Zenith Clinical Research — Hollywood, Florida
- Encore Medical Research LLC — Hollywood, Florida
- East Coast Institute for Research, LLC — Jacksonville, Florida
📞 Contact the Study Coordinator
Phone: (866) 572-6436
Email: medinfo@amgen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease — Birmingham, Alabama
- Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease — Birmingham, Alabama
- Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial — Birmingham, Alabama
- Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE — Memphis, Tennessee
Explore by condition: All Atherosclerotic Cardiovascular Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.