๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-16

TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas (NCT07082803)

An Open-Label, Multicenter, Phase 1 Trial to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of TLN-121 as a Single Agent and in Combination With Other Anti-Lymphoma Agents, in Patients With Relapsed or Refractory Non-Hodgkin Lymphomas

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Treeline Biosciences, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary purpose of this study is to evaluate the safety, pharmacokinetics,, and preliminary anti-tumor activity of TLN-121 as a single agent and in combination with other anti-lymphoma therapies in patients with relapsed or refractory Non-Hodgkin Lymphomas

Who can join: Review the eligibility criteria below.

Location: Stanford Medicine Cancer Center โ€” Palo Alto, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (14 Sites)

  • Stanford Medicine Cancer Center โ€” Palo Alto, California
  • The START Center for Cancer Care - Midwest โ€” Grand Rapids, Michigan
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Weill Cornell Medicine - New York Presbyterian Hospital โ€” New York, New York
  • Hospital of the University of Pennsylvania โ€” Philadelphia, Pennsylvania
  • SCRI Oncology Partners โ€” Nashville, Tennessee
  • The University of Texas MD Anderson Cancer Center โ€” Houston, Texas
  • Macquarie University Hospital โ€” Macquarie Park, New South Wales
  • Princess Alexandra Hospital โ€” Woolloongabba, Queensland
  • Cabrini Health โ€” Malvern, Victoria
  • Peter MacCallum Cancer Centre โ€” Melbourne, Victoria
  • Linear Clinical Research โ€” Perth, Western Australia
  • BC Cancer - Vancouver โ€” Vancouver, British Columbia

๐Ÿ“ž Contact the Study Coordinator

Phone: (857) 228-0050

Email: clinicaloperations@treeline.bio

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Lymphoma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—