๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-02

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors (NCT07107230)

A Phase 1 Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to determine recommended phase 2 doses (RP2Ds) of JNJ-95437446 in Part 1, and to further evaluate the safety of the RP2Ds in participants with advanced solid tumors in Part 2.

Who can join: Review the eligibility criteria below.

Location: Florida Cancer Specialists โ€” Sarasota, Florida

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (10 Sites)

  • Florida Cancer Specialists โ€” Sarasota, Florida
  • Columbia University Medical Center Herbert Irving Pavilion โ€” New York, New York
  • Tennessee Oncology โ€” Nashville, Tennessee
  • NEXT Oncology โ€” Fairfax, Virginia
  • Severance Hospital Yonsei University Health System โ€” Seoul,
  • Samsung Medical Center โ€” Seoul,
  • Hosp Univ Vall D Hebron โ€” Barcelona,
  • Hosp Univ Fund Jimenez Diaz โ€” Madrid,
  • Hosp. Univ. 12 de Octubre โ€” Madrid,
  • Hosp Univ Hm Sanchinarro โ€” Madrid,

๐Ÿ“ž Contact the Study Coordinator

Phone: (844) 434-4210

Email: Participate-In-This-Study1@its.jnj.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—