Modulation of Brain Rhythms in Stroke (NCT07121582)
Modulation of Beta Oscillatory Rhythms in Stroke to Promote Corticomuscular Circuit Function
🩺 Plain-English Summary (8th-Grade Level)
The goal of this research study is to examine communication between brain and muscle in individuals with stroke and determine if applying non-invasive brain stimulation to different parts of the brain improves this communication and performance on a hand squeezing task. The investigators will fit participants with an electroencephalography (EEG) cap and place electromyography (EMG) stickers on participants hand and arm muscles to record brain and muscle activity, respectively. Participants will complete a single research visit lasting approximately 3 hours. During this visit, participants will receive two different types of non-invasive brain stimulation: \[1\] stimulation to the motor part of the brain and \[2\] stimulation to the visual part of the brain. Participants will be randomized so that half will receive stimulation to the motor part of the brain first followed by stimulation to the visual part of the brain second and vice versa. Participants will complete three blocks of hand squeezing trials using the stroke-affected (weak) hand. During the first block of squeezing trials, no brain stimulation will occur. During the second and third blocks, participants will receive stimulation just before each hand squeezing trial. The investigators will record participants' brain and muscle activity during these blocks of hand squeezing trials. Additionally, participants will also complete screening tests and exams looking at mood, motor function, and cognition.
Who can join: Review the eligibility criteria below.
Location: Bondurant Hall — Chapel Hill, North Carolina
Age range: 45 Years to 80 Years
🧪 Interventions in This Study
- Motor Brain Stimulation (OTHER)
- Visual Brain Stimulation (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Bondurant Hall — Chapel Hill, North Carolina
📞 Contact the Study Coordinator
Phone: (919) 966-8404
Email: CassidyLab@unc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Stroke
- Validation of a Spasticity Measurement Tool — Chicago, Illinois
- GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors. — Boston, Massachusetts
- Determining the Optimal Dose of Reactive Balance Training After Stroke — Toronto, Ontario
- AMPLATZER PFO Occluder Post Approval Study — Birmingham, Alabama
- Reflex Excitability in Post-stroke Stiff-Knee Gait — Cleveland, Ohio
- Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA) — Dallas, Texas
Explore by condition: All Stroke clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.