OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events (NCT07136012)
A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing Olpasiran Use to Prevent First Major Cardiovascular Events in Participants With Elevated Lipoprotein(a)
🩺 Plain-English Summary (8th-Grade Level)
The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants at risk for a first major cardiovascular event with elevated lipoprotein(a) (Lp\[a\]).
Who can join: Review the eligibility criteria below.
Location: Advanced Cardiovascular LLC — Alexander City, Alabama
Age range: 50 Years to 105 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (252 Sites)
Showing the first 25 of 252 sites.
- Advanced Cardiovascular LLC — Alexander City, Alabama
- University of Alabama Birmingham Saint Vincents Birmingham — Birmingham, Alabama
- Birmingham Clinical Research — Birmingham, Alabama
- Alliance For Multispecialty Research - Daphne — Daphne, Alabama
- Eastern Shore Research Institute — Fairhope, Alabama
- Heart Center Research LLC — Huntsville, Alabama
- CB Flock Research Corporation — Mobile, Alabama
- Phoenix Clinical — Phoenix, Arizona
- Elite Clinical Studies LLC — Phoenix, Arizona
- Hero Clinical Research — Phoenix, Arizona
- HonorHealth Research Institute — Scottsdale, Arizona
- Eclipse Clinical Research — Tucson, Arizona
- Lynn Institute of the Ozarks — Little Rock, Arkansas
- National Heart Institute — Beverly Hills, California
- 310 Clinical Research — Inglewood, California
- University of California San Diego — La Jolla, California
- InvivoCure — Los Angeles, California
- Valley Clinical Trials — Northridge, California
- Clinical Trials Research - Sacramento — Roseville, California
- Alliance Clinical Research — San Diego, California
- Encompass Clinical Research — Spring Valley, California
- Stanford Health Care — Stanford, California
- Manshadi Heart Institute — Stockton, California
- Blue Coast Cardiology — Vista, California
- Diablo Clinical Research — Walnut Creek, California
📞 Contact the Study Coordinator
Phone: (866) 572-6436
Email: medinfo@amgen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.