๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-04

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (NCT07170150)

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (MCI to Mild Dementia Due to AD)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Hoffmann-La Roche

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).

Who can join: Review the eligibility criteria below.

Location: Banner Alzheimer?s Institute โ€” Phoenix, Arizona

Age range: 50 Years to 90 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (150 Sites)

Showing the first 25 of 150 sites.

  • Banner Alzheimer?s Institute โ€” Phoenix, Arizona
  • Sun Valley Research Center, Inc. โ€” Imperial, California
  • Healthy Brain Clinic โ€” Long Beach, California
  • Oakland Clinical โ€” Oakland, California
  • Riverside Clinical โ€” Riverside, California
  • Cenexel California Neuroscience Research, LLC โ€” Sherman Oaks, California
  • Yale University โ€” New Haven, Connecticut
  • JEM Research LLC โ€” Atlantis, Florida
  • K2 Medical Research-Winter Garden โ€” Clermont, Florida
  • Visionary Investigators Network- Neurology Aventura โ€” Miami, Florida
  • Charter Research - Winter Park/Orlando โ€” Orlando, Florida
  • Conquest Research - Lake Nona โ€” Orlando, Florida
  • Alzheimer's Research and Treatment Center โ€” Stuart, Florida
  • CenExel iResearch, LLC โ€” Decatur, Georgia
  • Center for Advanced Research & Education โ€” Gainesville, Georgia
  • Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville โ€” Chicago, Illinois
  • Adams Clinical Boston โ€” Boston, Massachusetts
  • Adams Clinical Watertown โ€” Watertown, Massachusetts
  • Quest Research Institute โ€” Farmington Hills, Michigan
  • University of Nebraska Medical Center โ€” Omaha, Nebraska
  • The Cognitive and Research Center of New Jersey โ€” Springfield, New Jersey
  • IMA Clinical Research - Albuquerque โ€” Albuquerque, New Mexico
  • AD-CARE, University of Rochester Medical Center โ€” Rochester, New York
  • Summit Research Network Inc. โ€” Portland, Oregon
  • Flourish Research ? Philadelphia โ€” Plymouth Meeting, Pennsylvania

๐Ÿ“ž Contact the Study Coordinator

Phone: (888) 662-6728

Email: global-roche-genentech-trials@gene.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—