Accelerated High-Dose tDCS for Depression (NCT07226011)
Accelerated High-Dose tDCS for Depression: An Open-Label Outpatient Pilot Study
🩺 Plain-English Summary (8th-Grade Level)
In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulation through electrodes placed on their scalp. The study begins with a safety run-in, where the first few participants will receive stimulation at gradually increasing levels (2, 4, and 6 milliamps) while being closely monitored. If no serious side effects are found, later participants will receive repeated 6 milliamp sessions for 5 days total. Investigators will check skin comfort, mood, and overall tolerability after each session.
Who can join: Review the eligibility criteria below.
Location: MUSC Brain Stimulation Lab — Charleston, South Carolina
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- MUSC Brain Stimulation Lab — Charleston, South Carolina
📞 Contact the Study Coordinator
Phone: (502) 377-8275
Email: olash@musc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Major Depression
- Study of Psilocybin Under Anesthesia Controlled by EEG — Stanford, California
- Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder — Belmont, Massachusetts
- Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101 — Belmont, Massachusetts
- Leucine in Midlife Depression — Atlanta, Georgia
- Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project — San Francisco, California
- Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression — Belmont, Massachusetts
Explore by condition: All Major Depression clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.