๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-02

Detection of Minimal Residual Disease Using Exosomal miRNA Distant Metastasis Markers (NCT07243015)

Exosomal microRNA-based Analysis for Early detectIon of Gastric Cancer Hidden-recurrence Traces

๐ŸŸข Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: City of Hope Medical Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Gastric cancer (GC) is a leading cause of cancer-related death worldwide. Even in patients undergoing curative surgery for non-metastatic disease, postoperative recurrence frequently occurs due to undetected minimal residual disease (MRD). This study aims to establish a highly sensitive and specific liquid biopsy assay using exosomal microRNAs (exo-miRNAs) to detect MRD and predict distant metastasis before clinical recurrence.

Who can join: Review the eligibility criteria below.

Location: City of Hope Medical Center โ€” Duarte, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • small RNA-seq or array (DIAGNOSTIC_TEST)
  • ENLIGHT Assay (DIAGNOSTIC_TEST)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • City of Hope Medical Center โ€” Duarte, California

๐Ÿ“ž Contact the Study Coordinator

Phone: (626) 218-3452

Email: ajgoel@coh.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Gastric Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—