Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis (NCT07298395)
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 12-Week Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ENV-294 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to learn about the safety and effectiveness of ENV-294 in adults with moderate to severe atopic dermatitis. The main questions it will answer are: * Is there an impact on the severity and area of atopic dermatitis when participants take ENV-294 * What medical problems do participants have when taking ENV-294 Participants will: * Take drug ENV-294 or a placebo once every day for 12 weeks * Visit the clinic every 2 to 4 weeks for checkups and tests * Keep a diary of their symptoms and when they took their study drug * Return to the clinic for the final study visit at approximately week 16
Who can join: Review the eligibility criteria below.
Location: Enveda Investigative Site — Birmingham, Alabama
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (32 Sites)
Showing the first 25 of 32 sites.
- Enveda Investigative Site — Birmingham, Alabama
- Enveda Investigative Site — Hot Springs, Arkansas
- Enveda Investigative Site — Beverly Hills, California
- Enveda Investigative Site — Fremont, California
- Enveda Investigative Site — San Diego, California
- Enveda Investigative Site — San Diego, California
- Enveda Investigative Site — Santa Monica, California
- Enveda Investigative Site — West Hills, California
- Enveda Investigative Site — Fort Lauderdale, Florida
- Enveda Investigative Site — Miami, Florida
- Enveda Investigative Site — Miramar, Florida
- Enveda Investigative Site — Atlanta, Georgia
- Enveda Investigative Site — Chicago, Illinois
- Enveda Investigative Site — Clarksville, Indiana
- Enveda Investigative Site — New Albany, Indiana
- Enveda Investigative Site — West Lafayette, Indiana
- Enveda Investigative Site — Louisville, Kentucky
- Enveda Investigative Site — Louisville, Kentucky
- Enveda Investigative Site — Auburn Hills, Michigan
- Enveda Investigative Site — Bay City, Michigan
- Enveda Investigative Site — Clinton Township, Michigan
- Enveda Investigative Site — Warren, Michigan
- Enveda Investigative Site — Las Vegas, Nevada
- Enveda Investigative Site — New York, New York
- Enveda Investigative Site — Wilmington, North Carolina
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atopic Dermatitis (AD)
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- A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis — Phoenix, Arizona
- Moisturization and Skin Hydration Study — Vancouver, British Columbia
- Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis — Fargo, North Dakota
- The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis — Pittsburgh, Pennsylvania
- Effect of an Emollient Cream Containing a Milk Bioactive Peptide on Clinical Signs, Pruritus and Bacterial Colonization of Mild Atopic Dermatitis Skin Lesions in Pediatric Population — Aguascalientes, Aguascalientes
Explore by condition: All Atopic Dermatitis (AD) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.