Safety and Efficacy of J147 in Acute Ischemic Stroke (NCT07430917)
A Phase II, Randomized, Placebo-Controlled, Double-Blind, Adaptive Study to Assess the Safety and Efficacy of Intravenous J147 Combined With Endovascular Therapy in Patients With Acute Ischemic Stroke
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to find out if the drug J147 improves outcomes for persons who have had an ischemic stroke. It also will learn about the safety of J147 when given by injection to stroke patients. Researchers will compare the outcomes of those who receive J147 after therapy to clear the blood clot to those who don't receive J147. Participants will be asked to undergo a series of three to four magnetic resonance imaging (MRI) brain scans, and blood samples will be collected at several time points. Participants will also be evaluated to measure several aspects of brain function.
Who can join: Review the eligibility criteria below.
Location: MemorialCare Long Beach Medical Center — Long Beach, California
Age range: 18 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- MemorialCare Long Beach Medical Center — Long Beach, California
- Javon Bea Hospital — Rockford, Illinois
- Albany Medical Center — Albany, New York
- Oregon Health and Science University — Portland, Oregon
- Dell Seton Medical Center at the University of Texas at Austin — Austin, Texas
📞 Contact the Study Coordinator
Phone: (619) 278-9516
Email: mprior@abrexa.net
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Ischemic Stroke
- EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial) — Little Rock, Arkansas
- PET Perfusion Imaging Techniques and Comparing Them to CT Perfusion Imaging in Stroke — Edmonton, Alberta
- An EFS to Evaluate the CGuard Prime™ Carotid Stent in Acute Ischemic Stroke — Buffalo, New York
- Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First Dose — Houston, Texas
- Efficacy and Safety of Xinglou Chengqi Granule for Acute Ischemic Stroke — Richmond, British Columbia
- Quelling of Excitotoxicity in Acute Stroke With Ketamine — Wynnewood, Pennsylvania
Explore by condition: All Acute Ischemic Stroke clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.