Duloxetine in Inflammatory Bowel Diseases (NCT07431606)
A Phase II Open-label Study of Duloxetine to Reduce Inflammatory Bowel Disease-Related Disability and Psychological Distress
๐ฉบ Plain-English Summary (8th-Grade Level)
This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflammatory bowel disease (IBD). The study focuses on patient-reported outcomes related to anxiety, depression, and IBD-related disability, aiming to assess feasibility, tolerability, and preliminary efficacy in modulating gut-brain axis symptoms and disease-related functional impairments in life
Who can join: Review the eligibility criteria below.
Location: University of Pennsylvania โ Philadelphia, Pennsylvania
Age range: 24 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- University of Pennsylvania โ Philadelphia, Pennsylvania
๐ Contact the Study Coordinator
Phone: (215) 349-8222
Email: Chung.Tse@Pennmedicine.upenn.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Inflammatory Bowel Diseases
- Implementing a Multimodal RCT Intervention to Improve the Transition of Patients With Crohn's Disease From Pediatric to Adult Care โ Vancouver, British Columbia
- PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFฮฑ Crohn's Disease ThErapy in Children: The PROMOTE Trial โ Ottawa, Ontario
- A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy โ Baltimore, Maryland
- Outpatient VR (Virtual Reality)-Brain-gut Behavioral Therapies (BGBT) in Inflammatory Bowel Disease (IBD) โ Ann Arbor, Michigan
- A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease โ Lancaster, California
- A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC โ Sun City, Arizona
Explore by condition: All Inflammatory Bowel Diseases clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.