A Study to Learn About mRNA Vaccines Against Influenza in Adults (NCT07431853)
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, CLINICAL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF MRNA VACCINES AGAINST INFLUENZA IN ADULTS 18 YEARS OF AGE AND OLDER
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus). This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison. Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.
Who can join: Review the eligibility criteria below.
Location: AMR Clinical — Mobile, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (15 Sites)
- AMR Clinical — Mobile, Alabama
- Diablo Clinical Research, LLC d/b/a Flourish Research — Walnut Creek, California
- Clinical Research Consulting, LLC — Milford, Connecticut
- George Washington Medical Faculty Associates — Washington D.C., District of Columbia
- Indago Research & Health Center, Inc — Hialeah, Florida
- Palm Springs Community Health Center — Miami Lakes, Florida
- Clinical Research Atlanta — Stockbridge, Georgia
- East-West Medical Research Institute — Honolulu, Hawaii
- AMR Clinical — Kansas City, Missouri
- Rochester Clinical Research, LLC — Rochester, New York
- DM Clinical Research - Philadelphia — Philadelphia, Pennsylvania
- SMS Clinical Research LLC — Mesquite, Texas
- DM Clinical Research — Tomball, Texas
- J. Lewis Research, Inc. / Foothill Family Clinic — Salt Lake City, Utah
- Charlottesville Medical Research Center, LLC — Charlottesville, Virginia
📞 Contact the Study Coordinator
Phone: (800) 718-1021
Email: ClinicalTrials.gov_Inquiries@pfizer.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.