๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-20

Study of INCA036978 in Participants With Myeloproliferative Neoplasms (NCT07441694)

A Phase 1, Open-Label, Multicenter Study of INCA036978 in Participants With Myeloproliferative Neoplasms

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Incyte Corporation

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study will be conducted to determine the safety, tolerability, dose-limiting toxicity (DLT)s, and maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE)s of INCA036978 administered as monotherapy and in combination with a standard disease-directed therapy.

Who can join: Review the eligibility criteria below.

Location: University of Alabama At Birmingham โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (54 Sites)

Showing the first 25 of 54 sites.

  • University of Alabama At Birmingham โ€” Birmingham, Alabama
  • City of Hope-Lennar Foundation Cancer Center โ€” Irvine, California
  • Usc Norris Comprehensive Cancer Center โ€” Los Angeles, California
  • UCLA Medical Hematology & Oncology โ€” Los Angeles, California
  • Yale Cancer Center โ€” New Haven, Connecticut
  • University of Miami โ€” Miami, Florida
  • Moffitt Cancer Center โ€” Tampa, Florida
  • Winship Cancer Institute of Emory University โ€” Atlanta, Georgia
  • John Hopkins Hospital โ€” Baltimore, Maryland
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Mount Sinai School of Medicine โ€” New York, New York
  • Weill Cornell Medicine โ€” New York, New York
  • University of North Carolina At Chapel Hill โ€” Chapel Hill, North Carolina
  • Levine Cancer Institute โ€” Charlotte, North Carolina
  • Duke University Medical Center, Department of Hematologic Malignancies and Cellular Therapy โ€” Durham, North Carolina
  • Cleveland Clinic โ€” Cleveland, Ohio
  • Ohio State University โ€” Columbus, Ohio
  • Tristar Bmt/Tcto โ€” Nashville, Tennessee
  • University of Texas M. D. Anderson Cancer Center โ€” Houston, Texas
  • Huntsman Cancer Institute โ€” Salt Lake City, Utah
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin
  • Concord General Repatriation Hospital โ€” Concord, New South Wales
  • Royal North Shore Hospital โ€” St Leonards, New South Wales

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 463-3463

Email: medinfo@incyte.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—