Protecting the Brain From Post-Stroke Cognitive Impairment and Dementia With Multimodal Exercise Training (NCT07445841)
Protecting the Brain From Post-Stroke Cognitive Impairment and Dementia With Multimodal Exercise Training: A Bayesian Adaptive Trial (PROTECT)
🩺 Plain-English Summary (8th-Grade Level)
The rates of cognitive decline and dementia after stroke are disproportionately high. Strategies that can protect the brain early after the stroke event could reduce the future risk of cognitive decline and dementia in these patients. Although physical exercise is usually recommended after stroke, there is very little information about the protective effect of exercise implemented in early stages of recovery as a potential protective measure against cognitive decline and dementia risk in these patients. This study will investigate the effect of a multimodal exercise intervention implemented early after the stroke event on cognition and on a selected group of markers that can predict cognitive decline and dementia risk.
Who can join: Review the eligibility criteria below.
Location: McMaster University — Hamilton, Ontario
Age range: 40 Years to 80 Years
🧪 Interventions in This Study
- Multimodal Training (OTHER)
- Balance, Toning and Stretching (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- McMaster University — Hamilton, Ontario
- Jewish Rehabilitation Hospital — Laval, Quebec
📞 Contact the Study Coordinator
Phone: (514) 398-4400
Email: marc.roigpull@mcgill.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Stroke
- Validation of a Spasticity Measurement Tool — Chicago, Illinois
- GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors. — Boston, Massachusetts
- Determining the Optimal Dose of Reactive Balance Training After Stroke — Toronto, Ontario
- AMPLATZER PFO Occluder Post Approval Study — Birmingham, Alabama
- Reflex Excitability in Post-stroke Stiff-Knee Gait — Cleveland, Ohio
- Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA) — Dallas, Texas
Explore by condition: All Stroke clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.