A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma (NCT07456033)
The MODIFY Study: A Phase 3b/4 Randomized, Double-blind, Placebo-controlled, Multi-centre Study Evaluating the Impact of Early Intervention With Depemokimab on Exacerbation Rate, Clinical Remission, Lung Function Decline, and Safety in Adults and Adolescents With at Risk Type 2 Asthma, Conducted up to 156 Weeks
🩺 Plain-English Summary (8th-Grade Level)
The aim of this study is to evaluate the efficacy of depemokimab administered as an adjunctive therapy, in participants with Type 2 asthma at risk of exacerbations compared to the guideline recommended standard of care (SoC).
Who can join: Review the eligibility criteria below.
Location: GSK Investigational Site — Little Rock, Arkansas
Age range: 12 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (17 Sites)
- GSK Investigational Site — Little Rock, Arkansas
- GSK Investigational Site — Newport Beach, California
- GSK Investigational Site — Aurora, Colorado
- GSK Investigational Site — Aventura, Florida
- GSK Investigational Site — Kissimmee, Florida
- GSK Investigational Site — Lake Worth, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Shreveport, Louisiana
- GSK Investigational Site — Oklahoma City, Oklahoma
- GSK Investigational Site — DuBois, Pennsylvania
- GSK Investigational Site — Wyomissing, Pennsylvania
- GSK Investigational Site — Rapid City, South Dakota
- GSK Investigational Site — San Antonio, Texas
- GSK Investigational Site — Burke, Virginia
- GSK Investigational Site — Bradford,
📞 Contact the Study Coordinator
Phone: (877) 379-3718
Email: GSKClinicalSupportHD@gsk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.