A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia (NCT07477704)
A Randomized, Open-Label, Dose-Ranging Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Weekly Alirocumab in Adults With Hypercholesterolemia
🩺 Plain-English Summary (8th-Grade Level)
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels). The aim of the study is to see how safe and effective alirocumab is when given weekly to adult participants who have hypercholesterolemia. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug once a week * How much study drug is in the blood at different times
Who can join: Review the eligibility criteria below.
Location: Pinnacle Research Group — Anniston, Alabama
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (34 Sites)
Showing the first 25 of 34 sites.
- Pinnacle Research Group — Anniston, Alabama
- Cullman Clinical Trials — Cullman, Alabama
- Anaheim Clinical Trials — Anaheim, California
- Cenexel CNS — Los Alamitos, California
- Diablo Clinical Research - Flourish Research — Walnut Creek, California
- Tampa Bay Medical Research — Clearwater, Florida
- Southwest General Healthcare Center — Fort Myers, Florida
- Precision Clinical Research — Sunrise, Florida
- K2 Medical Research The Villages — The Villages, Florida
- Center for Advanced Research and Education — Gainesville, Georgia
- Balanced Life Health Care Solutions — Lawrenceville, Georgia
- East-West Medical Research Institute — Honolulu, Hawaii
- L-MARC Research Center — Louisville, Kentucky
- Tandem Clinical Research — Marrero, Louisiana
- Mercury Street Medical Group, PLLC — Butte, Montana
- Velocity Clinical Research - Omaha — Omaha, Nebraska
- Palm Research Center, Mountainview Medical Center — Las Vegas, Nevada
- Velocity Clinical Research - Durham — Durham, North Carolina
- Accellacare of Wilmington — Wilmington, North Carolina
- Ohio Clinical Trials — Columbus, Ohio
- AMR Norman — Norman, Oklahoma
- Lynn Health Science Institute — Oklahoma City, Oklahoma
- Velocity Clinical Research, Medford — Medford, Oregon
- Altoona Center for Clinical Research — Duncansville, Pennsylvania
- Tribe Clinical Research — Greenville, South Carolina
📞 Contact the Study Coordinator
Phone: (844) 734-6643
Email: clinicaltrials@regeneron.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hypercholesterolemia
- Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension — Daphne, Alabama
- Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy — Baltimore, Maryland
- Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile — Addison, Illinois
- Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia — Clearwater, Florida
- Causes and Natural History of Dyslipidemias — Bethesda, Maryland
Explore by condition: All Hypercholesterolemia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.