Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis (NCT07556237)
🩺 Plain-English Summary (8th-Grade Level)
Gastroparesis is a disorder characterized by delayed gastric emptying and symptoms including nausea, vomiting, and abdominal pain. Gastric electrical stimulation (GES) using the implanted Enterra™ neurostimulator is FDA-approved to treat nausea and vomiting but its impact on abdominal pain has not been well studied. This study evaluates whether alternative programming parameters of the Enterra™ device can reduce abdominal pain in patients with gastroparesis. Participants with an existing Enterra™ device will be randomized to one of three stimulation settings and followed for assessment of pain, gastrointestinal symptoms, quality of life, and medication use.
Who can join: Review the eligibility criteria below.
Location: University of Louisville Clinical Trials Unit — Louisville, Kentucky
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Louisville Clinical Trials Unit — Louisville, Kentucky
📞 Contact the Study Coordinator
Phone: (502) 588-4600
Email: thomas.abell@louisville.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Gastroparesis
- Cardiac Vagal Effects of GES in Patients With Gastroparesis and Vagal Nerve Action Potentials in Vagus Nerve — Indianapolis, Indiana
- Vagus Nerve Response in Gastroparesis Patients — Indianapolis, Indiana
- ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve — Indianapolis, Indiana
- Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator — Dallas, Texas
- Magnetic Resonance Imaging of the Brain and Stomach in Healthy Volunteers and Gastroparesis — Indianapolis, Indiana
- Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial — Cleveland, Ohio
Explore by condition: All Gastroparesis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.