A Study to Assess the Safety, Tolerability and Efficacy of ION775 (NCT07604974)
A Phase 2, Open-label Trial Evaluating the Safety, Tolerability and Efficacy of ION775 in Adults With Hypertriglyceridemia
🩺 Plain-English Summary (8th-Grade Level)
The main objective of this study is to evaluate the effect of ION775 on fasting triglyceride (TG) levels in participants with hypertriglyceridemia (HTG) and severe hypertriglyceridemia (sHTG).
Who can join: Review the eligibility criteria below.
Location: Ionis Investigative Site — Lincoln, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- Ionis Investigative Site — Lincoln, California
- Ionis Investigative Site — Aurora, Colorado
- Ionis Investigative Site — Boca Raton, Florida
- Ionis Investigative Site — Miami, Florida
- Ionis Investigative Site — Miramar, Florida
- Ionis Investigative Site — Columbus, Georgia
- Ionis Investigative Site — Louisville, Kentucky
- Ionis Investigative Site — Flint, Michigan
- Ionis Investigative Site — Munroe Falls, Ohio
- Ionis Investigative Site — Little River, South Carolina
- Ionis Investigative Site — Houston, Texas
- Ionis Investigative Site — Lampasas, Texas
- Ionis Investigative Site — McKinney, Texas
- Ionis Investigative Site — Mesquite, Texas
- Ionis Investigative Site — San Antonio, Texas
- Ionis Investigative Site — Québec,
📞 Contact the Study Coordinator
Phone: (844) 828-3770
Email: IonisION775-CS2@clinicaltrialmedia.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hypertriglyceridemia
- Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia — Birmingham, Alabama
- Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects — Tamarac, Florida
- Evaluation of the Efficacy of Phospholipid-Bound Omega-3 Versus Omega-3 Alone in Patients With Hypertriglyceridemia: A Randomized Clinical Trial — Barranquilla, Atlántico
- Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD — Guadalajara, Jalisco
- A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol — Chula Vista, California
- Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol — Anniston, Alabama
Explore by condition: All Hypertriglyceridemia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.