Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes (NCT07685808)
A Phase 2, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of Olatorepatide, a GLP-1/GIP Receptor Agonist, With Different Doses and Drug-Titration Algorithms in Participants Living With Overweight or Obesity
🩺 Plain-English Summary (8th-Grade Level)
This study will test an experimental drug called olatorepatide ("study drug") to determine how safe and effective this drug is compared to placebo and how easily the body can accept this drug at different doses and dosing schedules without causing side effects, as well as how the drug is processed in the body by participants with overweight or obesity but do not have diabetes. The study is looking at: * What side effects the study drug might cause * How much study drug is in the blood at different times * How well the study drug works * What effects the study drug may have on the body at different dosing schedules * If the body makes antibodies to the study drug as this may cause the study drug to not work as well
Who can join: Review the eligibility criteria below.
Location: Diablo Clinical Research - Flourish Research — Walnut Creek, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- Diablo Clinical Research - Flourish Research — Walnut Creek, California
- K2 Medical Research Maitland LLC, Main Office — Maitland, Florida
- Charter Research LLC - The Villages — The Villages, Florida
- Clinical Site Partners, LLC DBA Flourish Research — Winter Park, Florida
- AMR Clinical - Lexington — Lexington, Kentucky
📞 Contact the Study Coordinator
Phone: (844) 734-6643
Email: clinicaltrials@regeneron.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Overweight or Obesity
- A Study of LY4064912 in Healthy Participants and With Overweight or Obesity — Los Alamitos, California
- Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US — Walnut Creek, California
- PA Moves Trial - Patient Participants — Pittsburgh, Pennsylvania
- Berries, Inflammation, and Gut Microbiome — Chicago, Illinois
- Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women — Birmingham, Alabama
- The Effects of Long-term Consumption of Full-fat Dairy Products on Satiety, Body Weight and Glycemic Control — Halifax, Nova Scotia
Explore by condition: All Overweight or Obesity clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.