Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy (NCT07711327)
🩺 Plain-English Summary (8th-Grade Level)
This study looks at how often atrial fibrillation (AF), an irregular heart rhythm, occurs in people with certain blood cancers who are starting a type of cancer medicine called a Bruton's tyrosine kinase inhibitor (BTKI). Researchers will follow 400 people starting BTKI therapy and compare them to 100 people with similar blood cancers who are not taking a BTKI. Participants will wear a smartwatch and, later, a heart monitor patch to check for AF and other irregular heart rhythms over 12 months. The study will also look at whether AF affects cancer treatment, such as needing to pause, lower the dose, or stop the BTKI, and whether it leads to other health problems such as bleeding, stroke, or heart-related hospital visits.
Who can join: Review the eligibility criteria below.
Location: City of Hope — Duarte, California
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- City of Hope — Duarte, California
- UC San Diego Health — San Diego, California
- Stanford Health Care — Stanford, California
📞 Contact the Study Coordinator
Phone: (707) 628-2150
Email: danieljg@stanford.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atrial Fibrillation (AF)
- Detection and Classification of Cardiac Rhythm and Atrial Fibrillation Using a Finger-worn Ring — La Jolla, California
- Phase-Aligned Atrial Fibrillation Mapping — Cleveland, Ohio
- Left Atrial Pressure-Guided Heart Failure Optimization During Atrial Fibrillation Ablation (LAP AF-HF) — Milwaukee, Wisconsin
- AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment — Los Angeles, California
- P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation — Paramus, New Jersey
- Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation — Huntsville, Alabama
Explore by condition: All Atrial Fibrillation (AF) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.