117 Recruiting Head and Neck Squamous Cell Carcinoma Clinical Trials
Explore open interventional and observational research studies actively enrolling participants across the USA. Verify eligibility and contact site coordinators directly.
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Top Recruiting Head and Neck Squamous Cell Carcinoma Studies
Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
📍 Exelixis Clinical Site #2 — Fullerton, California
View Study & Checklist ➔Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
📍 City of Hope Comprehensive Cancer Center — Duarte, California
View Study & Checklist ➔MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
📍 Banner MD Anderson Cancer Center — Gilbert, Arizona
View Study & Checklist ➔Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01
📍 Siteman Cancer Center — St Louis, Missouri
View Study & Checklist ➔Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial
📍 Roswell Park Cancer Institute — Buffalo, New York
View Study & Checklist ➔Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca
📍 Johns Hopkins University — Baltimore, Maryland
View Study & Checklist ➔A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma
📍 Valkyrie Clinical Trials — Los Angeles, California
View Study & Checklist ➔Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
📍 Dana Farber Cancer Institute — Boston, Massachusetts
View Study & Checklist ➔Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer
📍 University of Arizona Cancer Center — Tucson, Arizona
View Study & Checklist ➔Avelumab, Cetuximab, and Palbociclib in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
📍 UC San Diego Moores Cancer Center — La Jolla, California
View Study & Checklist ➔Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
📍 University of Cincinnati Medical Center — Cincinnati, Ohio
View Study & Checklist ➔FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma
📍 Highlands Oncology - North Hills — Fayetteville, Arkansas
View Study & Checklist ➔CD40 Agonist and PD-1 Inhibitor in HNSCC
📍 University of Pennsylvania — Philadelphia, Pennsylvania
View Study & Checklist ➔Los Tres Paso: Neoadjuvant Palbociclib Monotherapy, Concurrent Chemoradiation Therapy, Adjuvant Palbociclib Monotherapy in Patients With p16INK4a Negative, HPV-Unrelated Head and Neck Squamous Cell Carcinoma
📍 Washington University School of Medicine — St Louis, Missouri
View Study & Checklist ➔A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone
📍 Norton Cancer Institute, Downtown — Louisville, Kentucky
View Study & Checklist ➔Phase II Study of Neoadjuvant Cetuximab and Cemiplimab in Patients Undergoing Surgery for HNSCC
📍 Moffitt Cancer Center — Tampa, Florida
View Study & Checklist ➔Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
📍 UW Carbone Cancer Center — Madison, Wisconsin
View Study & Checklist ➔Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
📍 USC / Norris Comprehensive Cancer Center — Los Angeles, California
View Study & Checklist ➔Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
📍 Washington University School of Medicine — St Louis, Missouri
View Study & Checklist ➔CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma
📍 Washington University School of Medicine — St Louis, Missouri
View Study & Checklist ➔Surgery and Reducing Ionizing Radiation of the Unknown Primary
📍 Royal Adelaide Hospital — Adelaide, South Australia
View Study & Checklist ➔3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial
📍 M D Anderson Cancer Center — Houston, Texas
View Study & Checklist ➔Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama
View Study & Checklist ➔A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)
📍 Site 160 — Mobile, Alabama
View Study & Checklist ➔Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients With Head and Neck Cancer
📍 Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee
View Study & Checklist ➔Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer
📍 UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care — Irvine, California
View Study & Checklist ➔(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma
📍 Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee
View Study & Checklist ➔Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality
📍 Sidney Kimmel Cancer Center at Thomas Jefferson University — Philadelphia, Pennsylvania
View Study & Checklist ➔Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study.
📍 MD Anderson Cancer Center — Houston, Texas
View Study & Checklist ➔A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
📍 City of Hope — Duarte, California
View Study & Checklist ➔Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer
📍 Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee
View Study & Checklist ➔Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer
📍 Wake Forest Baptist Comprehensive Cancer Center — Winston-Salem, North Carolina
View Study & Checklist ➔HN-QUEST: A Study of Head and Neck Imaging Biomarkers
📍 Princess Margaret Cancer Centre — Toronto, Ontario
View Study & Checklist ➔A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
📍 Site 164 — Mobile, Alabama
View Study & Checklist ➔Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).
📍 Sibley Memorial Hospital — Washington D.C., District of Columbia
View Study & Checklist ➔A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors
📍 LSU Health Sciences Center — Shreveport, Louisiana
View Study & Checklist ➔Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma
📍 UAB — Birmingham, Alabama
View Study & Checklist ➔A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC
📍 Moffitt Cancer Center — Tampa, Florida
View Study & Checklist ➔Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
📍 University Health Network, Princess Margaret Cancer Center — Toronto, Ontario
View Study & Checklist ➔