28 Paid Clinical Research Studies in Irvine, California
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
The purpose of this study is to learn about the safety and how effective the study medicine (PF-07220060) plus fulvestrant is compared to the study doctor's choice of treatment in
📍 Hoag Health Center Irvine — Irvine, California
View Study & Checklist ➔PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)
This Phase 1b study aims to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of multiple IV infusions of PMN310 in patients with earl
📍 Irvine Center for Clinical Research — Irvine, California
View Study & Checklist ➔Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
Optical coherence tomography guided laser treatment of basal cell carcinoma
📍 UCI Health Dermatology Clinic — Irvine, California
View Study & Checklist ➔A Study Comparing Two Types of Supportive Interventions for Caregivers of Patients With Cancer
The purpose of this study is to compare two types of therapy for caregivers of cancer patients: Emotion Regulation Therapy for Cancer Caregivers (ERT-C) and Cognitive Behavioral Th
📍 University of California, Irvine (Data and Specimen Analysis Only) — Irvine, California
View Study & Checklist ➔AMP SCZ® Observational Study: PREDICT-DPACC
The Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) is a large international collaboration to develop algorithms using a set of clinical and cognitive assessments, mul
📍 University of California Irvine — Irvine, California
View Study & Checklist ➔Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
We have recently developed and optimized a vaginal Optical Coherence tomography/angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the
📍 Beckman Laser Institute and Medical Clinic — Irvine, California
View Study & Checklist ➔Clinical Validation of the Norbert Health Device for Pulse Rate Measurement at Vigilant Clinical Testing
The study will evaluate the measuring pulse rate (PR) using the Norbert Device (ND) as compared to a reference heart rate measured using an electrocardiogram (ECG).
📍 Vigilant Clinical Testing — Irvine, California
View Study & Checklist ➔Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
The Skills-Based Educational strategies for Reduction of Vascular Events in Orange County, CA (SERVE OC) study aims to evaluate the efficacy of a culturally tailored, skills-based,
📍 University of California, Irvine — Irvine, California
View Study & Checklist ➔The Phase-2 CCR5-targeting Leronlimab With Oral Chemotherapy and VEGF-inhibitor Enriched Regimen Trial (CLOVER)
This is an open label, randomized, two arm, multi-center study to explore the effect of leronlimab on the overall response rate/ overall survival and safety and tolerability when u
📍 City of Hope Orange County Lennar Foundation Cancer Center — Irvine, California
View Study & Checklist ➔Metformin in Alzheimer's Dementia Prevention
MAP will be a multi-center phase 2/3 1:1 randomized controlled trial (RCT) of long-acting metformin (reduced mass Glucophage XR) vs. matching placebo in 326 men and women with earl
📍 University of California - Irvine — Irvine, California
View Study & Checklist ➔Skin Imaging With Technologies in Development
The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect infor
📍 Beckman Laser Institute Medical Clinic — Irvine, California
View Study & Checklist ➔A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases
The main aim of this study is to learn if TAK-881 is safe and well tolerated during long-term use in adults and children with PIDD who are eligible and completed study TAK-881-3001
📍 University of California, Irvine Medical Sciences I — Irvine, California
View Study & Checklist ➔A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
The purpose of this study is to learn about the safety and effects of the study medicine (called ritlecitinib) for the possible treatment of severe alopecia areata. Alopecia areata
📍 UCI Dermatology Clinical Research — Irvine, California
View Study & Checklist ➔Acupressure in Patients With Sickle Cell Disease
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).
📍 University of California, Irvine — Irvine, California
View Study & Checklist ➔Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry
The ULTRA Registry is a nationwide observational arm of the ULTRA trial. Data from the ULTRA Registry will be used to evaluate the long-term safety and efficacy of laparoscopic RF
📍 UC Irvine Medical Center — Irvine, California
View Study & Checklist ➔A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
The purpose of this Master Protocol is to support multiple studies looking at safety and tolerability of different drugs in healthy participants and participants with Alzheimer's d
📍 Irvine Clinical Research — Irvine, California
View Study & Checklist ➔A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
The purpose of this study is to see how safe LY4405094 is and to see how much and how quickly LY4405094 gets into the bloodstream. For healthy participants, the study also looks at
📍 Irvine Clinical Research — Irvine, California
View Study & Checklist ➔Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Knee Osteoarthritis
This is an multi-center study with the aim of evaluating the efficacy of adipose tissue processed with the SyntrFuge™ system in Orthopedic Surgery, specifically Knee Osteoarthritis
📍 Irvine Site 1 — Irvine, California
View Study & Checklist ➔A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimul
📍 Beckman Laser Institute and Medical Clinic — Irvine, California
View Study & Checklist ➔A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
This phase II trial compares the effect of ASTX727 in combination with iadademstat to ASTX727 alone in treating patients with accelerated or blast phase Philadelphia chromosome neg
📍 UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care — Irvine, California
View Study & Checklist ➔Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors
The goal of this clinical trial is to learn about HT-001 Topical Gel for treatment of EGFR inhibitor-induced skin toxicities. The main questions it aims to answer are: * Determine
📍 UCI Health - CIACC — Irvine, California
View Study & Checklist ➔The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of
📍 The Regents of the University of California, Irvine — Irvine, California
View Study & Checklist ➔Biomarker Exploration in Aging, Cognition and Neurodegeneration
The purpose of this research study is to understand the factors that underlie changes in thinking and memory with increasing age. The investigators will test the usefulness of MRI,
📍 University of California, Irvine — Irvine, California
View Study & Checklist ➔A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elderly population. Clinical symptoms of the disease m
📍 Irvine Center for Clinical Research /ID# 277752 — Irvine, California
View Study & Checklist ➔Intermuscular Coherence as a Biomarker for ALS
The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS. Specifical
📍 University of California Center for Clinical Research — Irvine, California
View Study & Checklist ➔Neural Bases of Vocal Sensorimotor Impairment in Aphasia
Aphasia is the most common type of post-stroke communication disorder characterized by deficits in speech comprehension, production and control. While recovery can be promoted with
📍 University of California Irvine — Irvine, California
View Study & Checklist ➔A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
This is a Phase 1, randomized, blinded, placebo controlled, single-ascending dose (SAD) and multiple-ascending dose (MAD) study of BBT001 in healthy volunteers (HVs) and adult pati
📍 First OC Dermatology — Irvine, California
View Study & Checklist ➔Using Nicotine to Reverse Age-related Auditory Processing Deficits
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participant
📍 Hearing and Speech Lab — Irvine, California
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