🏛️ Verified NIH Record • Updated 2026-08-04

Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer (NCT01081951)

A Phase II Open Label Randomised Comparative Multicentre Study to Compare the Efficacy and Tolerability of Olaparib in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Patients With Platinum Sensitive Advanced Serous Ovarian Cancer

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

To compare the efficacy of olaparib in combination with paclitaxel and carboplatin (AUC4) when compared with carboplatin (AUC6) and paclitaxel alone in patients with advanced ovarian cancer.

Who can join: Review the eligibility criteria below.

Location: Research Site — Stanford, California

Age range: 18 Years to 125 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (53 Sites)

Showing the first 25 of 53 sites.

  • Research Site — Stanford, California
  • Research Site — West Hollywood, California
  • Research Site — Orlando, Florida
  • Research Site — Indianapolis, Indiana
  • Research Site — Boston, Massachusetts
  • Research Site — Boston, Massachusetts
  • Research Site — New York, New York
  • Research Site — Portland, Oregon
  • Research Site — Parkville,
  • Research Site — Randwick,
  • Research Site — Brussels,
  • Research Site — Leuven,
  • Research Site — Namur,
  • Research Site — Wilrijk,
  • Research Site — Vancouver, British Columbia
  • Research Site — Hamilton, Ontario
  • Research Site — Toronto, Ontario
  • Research Site — Toronto, Ontario
  • Research Site — Québec, Quebec
  • Research Site — Sherbrooke, Quebec
  • Research Site — Brno,
  • Research Site — Brno,
  • Research Site — Hradec Králové,
  • Research Site — Olomouc,
  • Research Site — Prague,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Ovarian Cancer clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗