A Trial of Vigil for Participants With Ovarian Cancer (NCT02346747)
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of Vigil Engineered Autologous Tumor Cell Immunotherapy in Subjects With Stage IIIb-IV Ovarian Cancer in Clinical Complete Response Following Surgery and Primary Chemotherapy
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to compare participants with ovarian, fallopian tube or primary peritoneal cancer when treated with investigational product (Vigil) compared to placebo. The main question it aims to answer is "Will participants who receive treatment with Vigil have a longer time to disease recurrence versus the participants that were not given Vigil?"
Who can join: Review the eligibility criteria below.
Location: University of South Alabama Mitchell Cancer Institute — Mobile, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (26 Sites)
Showing the first 25 of 26 sites.
- University of South Alabama Mitchell Cancer Institute — Mobile, Alabama
- Southern California Permanente Medical Group — Irvine, California
- Palo Alto Foundation Medical Group — San Francisco, California
- University Of Miami Sylvester Comprehensive Cancer Center — Miami, Florida
- Moffitt Cancer Center — Tampa, Florida
- Florida Cancer Specialists — West Palm Beach, Florida
- Georgia Cancer Center at Augusta University — Augusta, Georgia
- University Of Kentucky Markey Cancer Center — Lexington, Kentucky
- Maine Medical Center: MMP Women's Health — Scarborough, Maine
- Dana Farber Cancer Institute: Gynecologic Oncology — Boston, Massachusetts
- Henry Ford Health System — Detroit, Michigan
- Billings Clinic — Billings, Montana
- Nebraska Methodist Hospital — Omaha, Nebraska
- Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center — Lebanon, New Hampshire
- University of New Mexico Cancer Center — Albuquerque, New Mexico
- Duke University Medical Center, Department of Medicine - Oncology — Durham, North Carolina
- Barrett Cancer Center University of Cincinnati Medical Center — Cincinnati, Ohio
- Stephenson Cancer Center at University of Oklahoma — Oklahoma City, Oklahoma
- AMD Asplundh Cancer Pavilion — Abington, Pennsylvania
- St. Luke's Health Network — Bethlehem, Pennsylvania
- Fox Chase Cancer Center — Philadelphia, Pennsylvania
- Prisma Health Cancer Institute — Greenville, South Carolina
- Mary Crowley Cancer Research Centers — Dallas, Texas
- University of Texas Southwestern Medical Center — Dallas, Texas
- Cancer Care Northwest — Spokane, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ovarian Cancer
- Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy — New York, New York
- Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer — Pittsburgh, Pennsylvania
- Trial on Radical Upfront Surgery in Advanced Ovarian Cancer — New York, New York
- Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) — Duarte, California
- Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302) — Little Rock, Arkansas
- NeoVax With Nivolumab in Patients With Ovarian Cancer — Boston, Massachusetts
Explore by condition: All Ovarian Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.