🏛️ Verified NIH Record • Updated 2026-06-10
JOURNEY™ II CR Total Knee System (NCT02440672)
A Prospective, Non-randomized, Single Cohort, Multicenter Study to Evaluate the Clinical Outcomes of Total Knee Arthroplasty (TKA) Using the JOURNEY™ II CR Total Knee System
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Smith & Nephew, Inc.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the safety and effectiveness of the JOURNEY™ II CR Total Knee System in subjects with degenerative joint disease (DJD) requiring primary total knee replacement.
Who can join: Review the eligibility criteria below.
Location: Orthopedic Institute of the West — Phoenix, Arizona
Age range: 22 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Orthopedic Institute of the West — Phoenix, Arizona
- Rush University Medical Center — Chicago, Illinois
- Anne Arundel Health System Research Institute, Inc — Annapolis, Maryland
- Center for Hip and Knee Replacement at Columbia University Medical Center — New York, New York
- Wake Forest University — Winston-Salem, North Carolina
- The Lindner Research Center, Musculo-Skeletal Division - The Christ Hospital Health Network — Cincinnati, Ohio
- Hospital Parc Taulí Servei de Cirurgia Ortopèdica I Traumatologia — Barcelona,
- Royal National Orthopaedic Hospital NHS Trust — Stanmore,
- Barts Health NHS Trust — Whitechapel,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.