A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433 (NCT03345823)

🧪 Interventions in This Study

• Upadacitinib (DRUG)
• Placebo for Upadacitinib (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (466 Sites)

Showing the first 25 of 466 sites.

• East View Medical Research, LLC /ID# 171132 — Mobile, Alabama
• CB Flock Research Corporation /ID# 166239 — Mobile, Alabama
• Delsol Research Management, Ll /Id# 170164 — Chandler, Arizona
• Duplicate_HonorHealth Research Institute - Shea /ID# 164725 — Scottsdale, Arizona
• Duplicate_Arizona Arthritis & Rheumatology Research, PLLC /ID# 164702 — Sun City, Arizona
• Southern California Res. Ctr. /ID# 169653 — Coronado, California
• Citrus Valley Gastroenterology /ID# 166230 — Covina, California
• Hoag Memorial Hosp Presbyterian /ID# 222538 — Irvine, California
• UC San Diego Health System /ID# 164763 — La Jolla, California
• United Medical Doctors /ID# 207458 — Los Alamitos, California
• Gastrointestinal Biosciences Clinical Trials, LLC /ID# 164640 — Los Angeles, California
• Facey Medical Foundation /ID# 203138 — Mission Hills, California
• United Medical Doctors - Murrieta /ID# 164602 — Murrieta, California
• Medical Assoc Research Grp /ID# 169704 — San Diego, California
• UCSF Medical Center - Mount Zion /ID# 202372 — San Francisco, California
• Univ of California San Francis /ID# 164653 — San Francisco, California
• Care Access Research /ID# 167765 — San Pablo, California
• Peak Gastroenterology Associates, PC /ID# 170166 — Colorado Springs, Colorado
• Delta Waves, Inc. /ID# 164656 — Colorado Springs, Colorado
• Western States Clinical Res /ID# 164625 — Wheat Ridge, Colorado
• Gastroenterology Center of Connecticut /ID# 164614 — Hamden, Connecticut
• Advanced Research - Coral Springs /ID# 218019 — Coral Springs, Florida
• Encore Borland-Groover Clinical Research /Id# 203500 — Jacksonville, Florida
• Ctr for Advanced Gastroenterol /ID# 165306 — Maitland, Florida
• Crystal Pharmacology Research /ID# 166118 — Miami, Florida

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Crohn's Disease

• A Non-Interventional Clinical Study to Evaluate Long-Term Safety and Effectiveness of HUMIRA (Adalimumab) in Pediatric Patients With Moderately to Severely Active Crohn's Disease (CD) — Birmingham, Alabama
• A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease — Birmingham, Alabama
• A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease. — Sun City, Arizona
• Study to Assess Speed of Onset and Durability of Effectiveness of Upadacitinib in Adult Participants With Moderate to Severe Crohn's Disease (CD) in Real World Clinical Practice. — Blacktown, New South Wales
• Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients — San Francisco, California
• Dietary Therapy and Gut Microbiome in Crohn's Disease and Ulcerative Colitis — Boston, Massachusetts

Explore by condition: All Crohn's Disease clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.