πŸ›οΈ Verified NIH Record β€’ Updated 2026-08-04

A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU) (NCT03459846)

A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients With Unresectable Stage IV Urothelial Cancer

πŸ”΅ Active, Not Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients With Unresectable Stage IV Urothelial Cancer

Who can join: Review the eligibility criteria below.

Location: Research Site β€” Birmingham, Alabama

Age range: 18 Years to 130 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (44 Sites)

Showing the first 25 of 44 sites.

  • Research Site β€” Birmingham, Alabama
  • Research Site β€” Goodyear, Arizona
  • Research Site β€” Fort Myers, Florida
  • Research Site β€” St. Petersburg, Florida
  • Research Site β€” Tampa, Florida
  • Research Site β€” Louisville, Kentucky
  • Research Site β€” New Hyde Park, New York
  • Research Site β€” New York, New York
  • Research Site β€” The Bronx, New York
  • Research Site β€” Philadelphia, Pennsylvania
  • Research Site β€” Nashville, Tennessee
  • Research Site β€” Tacoma, Washington
  • Research Site β€” Greater Sudbury, Ontario
  • Research Site β€” Hamilton, Ontario
  • Research Site β€” Newmarket, Ontario
  • Research Site β€” Toronto, Ontario
  • Research Site β€” Montreal, Quebec
  • Research Site β€” Moscow,
  • Research Site β€” Moscow,
  • Research Site β€” Novosibirsk,
  • Research Site β€” Omsk,
  • Research Site β€” Saint Petersburg,
  • Research Site β€” Saint Petersburg,
  • Research Site β€” Saint Petersburg,
  • Research Site β€” Incheon,

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—