A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU) (NCT03459846)
A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients With Unresectable Stage IV Urothelial Cancer
π©Ί Plain-English Summary (8th-Grade Level)
A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients With Unresectable Stage IV Urothelial Cancer
Who can join: Review the eligibility criteria below.
Location: Research Site β Birmingham, Alabama
Age range: 18 Years to 130 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (44 Sites)
Showing the first 25 of 44 sites.
- Research Site β Birmingham, Alabama
- Research Site β Goodyear, Arizona
- Research Site β Fort Myers, Florida
- Research Site β St. Petersburg, Florida
- Research Site β Tampa, Florida
- Research Site β Louisville, Kentucky
- Research Site β New Hyde Park, New York
- Research Site β New York, New York
- Research Site β The Bronx, New York
- Research Site β Philadelphia, Pennsylvania
- Research Site β Nashville, Tennessee
- Research Site β Tacoma, Washington
- Research Site β Greater Sudbury, Ontario
- Research Site β Hamilton, Ontario
- Research Site β Newmarket, Ontario
- Research Site β Toronto, Ontario
- Research Site β Montreal, Quebec
- Research Site β Moscow,
- Research Site β Moscow,
- Research Site β Novosibirsk,
- Research Site β Omsk,
- Research Site β Saint Petersburg,
- Research Site β Saint Petersburg,
- Research Site β Saint Petersburg,
- Research Site β Incheon,
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992) β Washington D.C., District of Columbia
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.