A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder (NCT04658862)
A Phase 3, Multi-center, Randomized Study Evaluating Efficacy of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-Invasive Urothelial Carcinoma (MIBC) of the Bladder Who Are Not Receiving Radical Cystectomy
π©Ί Plain-English Summary (8th-Grade Level)
The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with intravenous (IV) cetrelimab versus concurrent chemoradiotherapy.
Who can join: Review the eligibility criteria below.
Location: Loma Linda Univ Faculty Medic β Loma Linda, California
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (290 Sites)
Showing the first 25 of 290 sites.
- Loma Linda Univ Faculty Medic β Loma Linda, California
- University of Southern California β Los Angeles, California
- Providence Saint John s Health Center β Santa Monica, California
- Stanford University Medical Center β Stanford, California
- The Urology Center of Colorado β Denver, Colorado
- Foothills Urology - Golden Off β Golden, Colorado
- Boca Raton Regional Hospital β Boca Raton, Florida
- Urological Research Network β Hialeah, Florida
- Memorial Healthcare System β Pembroke Pines, Florida
- Winship Cancer Institute of Emory University β Atlanta, Georgia
- DuPage Medical Group β Lisle, Illinois
- University Hospitals Seidman Cancer Center β Ann Arbor, Michigan
- Michigan Institute of Urology β Troy, Michigan
- Adult Pediatric Urology & Urogynecology, P.C β Omaha, Nebraska
- Garden State Urology β Morristown, New Jersey
- New Jersey Urology LLC β Voorhees Township, New Jersey
- Cardiology Clinic at Montefiore Hutchinson Complex β The Bronx, New York
- Duke University Medical Center β Durham, North Carolina
- Vidant Urology - Greenville β Greenville, North Carolina
- Wake Forest University Baptist Medical Center (WFUBMC) - Comprehensive Cancer Center β Winston-Salem, North Carolina
- Wexner Medical Center at the Ohio State University β Columbus, Ohio
- Stephenson Cancer Center β Oklahoma City, Oklahoma
- MidLantic Urology β Bala-Cynwyd, Pennsylvania
- Carolina Urologic Research Center β Myrtle Beach, South Carolina
- University of Tennessee Medical Center β Knoxville, Tennessee
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-GuΓ©rin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy β Tucson, Arizona
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.