🏛️ Verified NIH Record • Updated 2025-09-12

Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease (NCT03485378)

Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease (ASPIRE-ILD): A Phase II Trial

🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

🩺 Plain-English Summary (8th-Grade Level)

This is a prospective phase II study of Stereotactic Ablative Radiotherapy (SABR) in patients with Non-Small Cell Lung Cancer (NSCLC) and co-existent Interstitial Lung Disease (ILD), to determine oncologic and toxicity outcomes. Patients will be divided into 3 separate cohorts based on the ILD-GAP index.

Who can join: Review the eligibility criteria below.

Location: Alberta Health Services, Cross Cancer Institude — Edmonton, Alberta

Age range: 18 Years

🧪 Interventions in This Study

  • Stereotactic Ablative Radiotherapy (RADIATION)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (6 Sites)

  • Alberta Health Services, Cross Cancer Institude — Edmonton, Alberta
  • London Regional Cancer Program of the Lawson Health Research Institute — London, Ontario
  • Sunnybrook Health Sciences Centre — Toronto, Ontario
  • UHN Princess Margaret Cancer Centre — Toronto, Ontario
  • CHUM Université de Montréal — Montreal, Quebec
  • Edinburgh Cancer Centre, Western General Hospital — Edinburgh,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗