Who is eligible for clinical trial NCT04736173?

Participants must meet protocol criteria for Non Small Cell Lung Cancer. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04736173 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-28

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer (NCT04736173)

Official Title: A Phase 2 Study to Evaluate Zimberelimab (AB122) Combined With AB154 in Front-Line, PD-L1-High, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Arcus Biosciences, Inc.

🩺 Plain-English Summary (8th-Grade Level)

This is a phase 2 study to evaluate zimberelimab (AB122) combined with domvanalimab (AB154) in front-line, PD-L1-high, locally advanced or metastatic Non-Small Cell Lung Cancer (NSCLC).

Who can join: Review the eligibility criteria below.

Location: Research Site — Columbus, Georgia

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (44 Sites)

Showing the first 25 of 44 sites.

Research Site — Columbus, Georgia
Research Site — Kingwood, Texas
Research Site — Blacksburg, Virginia
Research Site — Hong Kong,
Research Site — Johor Bahru,
Research Site — Kuala Lumpur,
Research Site — Kuantan,
Research Site — Kuching,
Research Site — Pulau Pinang,
Research Site — Putrajaya,
Research Site — Mexico City,
Research Site — San Luis Potosí City,
Research Site — Cebu,
Research Site — Davao City,
Research Site — Manila,
Research Site — Michalovce,
Research Site — George,
Research Site — Johannesburg,
Research Site — Pretoria,
Research Site — Busan,
Research Site — Daegu,
Research Site — Incheon,
Research Site — Jinju,
Research Site — Seoul,
Research Site — Suwon,

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC — Beverly Hills, California
Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease — Edmonton, Alberta
A Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast Cancer — Springdale, Arkansas

Explore by condition: All Non Small Cell Lung Cancer clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Review the official NIH record below to find the coordinating site.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗