Reducing Lung CongestIon Symptoms in Advanced Heart Failure (NCT03499236)
RELIEVE-HF TRIAL: REducing Lung congestIon Symptoms Using the v-wavE Shunt in adVancEd Heart Failure
🩺 Plain-English Summary (8th-Grade Level)
The objective of the RELIEVE-HF study is to provide reasonable assurance of safety and effectiveness of the V-Wave Interatrial Shunt System by improving meaningful clinical outcomes in patients with New York Heart Association (NYHA) functional Class II, Class III, or ambulatory Class IV heart failure (HF), irrespective of left ventricular ejection fraction, who at baseline are treated with guideline-directed drug and device therapies.
Who can join: Review the eligibility criteria below.
Location: Abrazo Arizona Heart Hospital — Phoenix, Arizona
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (83 Sites)
Showing the first 25 of 83 sites.
- Abrazo Arizona Heart Hospital — Phoenix, Arizona
- Arizona Heart Rhythm Center — Phoenix, Arizona
- Scripps Health — La Jolla, California
- Long Beach Memorial Medical Center — Long Beach, California
- Keck Medical Center of USC — Los Angeles, California
- Cedars Sinai Medical Center — Los Angeles, California
- Kaiser Permanente San Francisco — San Francisco, California
- University of California, San Francisco — San Francisco, California
- Stanford Hospital — Stanford, California
- Los Robles Hospital & Medical Center — Thousand Oaks, California
- The Lundquist Institute (Harbor-UCLA) Medical Center — Torrance, California
- South Denver Cardiology — Littleton, Colorado
- Memorial Hospital — Jacksonville, Florida
- University of Miami — Miami, Florida
- First Coast Cardiovascular Institute — Orange Park, Florida
- Piedmont Hospital — Atlanta, Georgia
- Northeast Georgia Medical Center — Gainesville, Georgia
- Rush University Medical Center — Chicago, Illinois
- Midwest Cardiovascular Institute — Naperville, Illinois
- St Elizabeth Medical Center — Edgewood, Kentucky
- United Heart & Vascular Clinic — Saint Paul, Minnesota
- Nebraska Heart Institute — Lincoln, Nebraska
- Valley Health System — Ridgewood, New Jersey
- Weill Cornell — New York, New York
- Rochester General Health System — Rochester, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Heart Failure
- REDUCE LAP-HFREF TRIAL — New York, New York
- Physiological Effects Ketone Ester in Heart — Cleveland, Ohio
- DASH Diet in Heart Failure Outpatients — Sacramento, California
- Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients — Huntsville, Alabama
- LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. — Birmingham, Alabama
- A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation — Alexander City, Alabama
Explore by condition: All Heart Failure clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.