A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2) (NCT04437511)
Assessment of Safety, Tolerability, and Efficacy of Donanemab in Early Symptomatic Alzheimer's Disease
🩺 Plain-English Summary (8th-Grade Level)
The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease. Additional participants will be enrolled to an addendum safety cohort. The participants will be administered open-label donanemab. Trial participants who were dosed with donanemab in the main study will be enrolled to a 3-year follow up addendum. No study drug will be administered during this follow up.
Who can join: Review the eligibility criteria below.
Location: Gilbert Neurology — Gilbert, Arizona
Age range: 60 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (274 Sites)
Showing the first 25 of 274 sites.
- Gilbert Neurology — Gilbert, Arizona
- Xenoscience — Phoenix, Arizona
- Banner Alzheimer's Institute — Phoenix, Arizona
- Perseverance Research Center — Scottsdale, Arizona
- Banner Sun Health Research Institute — Sun City, Arizona
- Banner Alzheimer's Institute Tucson — Tucson, Arizona
- Center for Neurosciences — Tucson, Arizona
- Health Initiatives Research — Fayetteville, Arkansas
- North County Neurology Associates — Carlsbad, California
- Wr- Pri, Llc — Encino, California
- Neuro-Pain Medical Center — Fresno, California
- Neurology Center of North Orange County — Fullerton, California
- Irvine Clinical Research — Irvine, California
- Kaizen Brain Center — La Jolla, California
- Senior Clinical Trials, Inc. — Laguna Hills, California
- Collaborative Neuroscience Research, LLC — Los Alamitos, California
- USC Keck School of Medicine — Los Angeles, California
- Clinical Research Institute — Los Angeles, California
- Neurovations — Napa, California
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- Stanford Neuroscience Health Center — Palo Alto, California
- SC3 Research - Pasadena — Pasadena, California
- PCND Neurology — Poway, California
- Anderson Clinical Research — Redlands, California
- Artemis Institute for Clinical Research — San Diego, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Alzheimer Disease
- The Use of Memantine for Prevention of Alzheimer's Disease — Charlottesville, Virginia
- Investigation of Inflammation Using [C-11]-CS1P1 — St Louis, Missouri
- Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia — Palo Alto, California
- A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study) — Gilbert, Arizona
- High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease — Cambridge, Massachusetts
- A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease — Phoenix, Arizona
Explore by condition: All Alzheimer Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.