Cardiac Rehab Effects in HFpEF (NCT04506606)
Efficacy of Exercise Training in Patients With HFpEF
🩺 Plain-English Summary (8th-Grade Level)
This research in Veterans with heart failure with preserved ejection fraction (HFpEF) will provide new information on the mechanisms determining the patients' exercise intolerance and the efficacy of regular physical activity to improve this shortcoming by alleviating the patients' neurocirculatory abnormalities. Specifically, the investigators will focus on the role of nerves originating in working limb muscles in determining the patients' exercise intolerance and compromised fatigue resistance before and after a chronic exercise intervention. By focusing on a specific mechanism, this project will evaluate the validity of exercise as an alternative treatment strategy with the overall purpose of improving the quality of life of Veterans with HFpEF.
Who can join: Review the eligibility criteria below.
Location: VA Salt Lake City Health Care System, Salt Lake City, UT — Salt Lake City, Utah
Age range: 21 Years to 85 Years
🧪 Interventions in This Study
- Afferent block (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- VA Salt Lake City Health Care System, Salt Lake City, UT — Salt Lake City, Utah
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Heart Failure With Preserved Ejection Fraction
- Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients — Baltimore, Maryland
- Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction — Naples, Florida
- IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency — Durham, North Carolina
- Matching Perfusion and Metabolic Activity in HFpEF — Philadelphia, Pennsylvania
- Exercise Lower-body Negative Pressure in Heart Failure With Preserved Ejection Fraction — Kelowna, British Columbia
Explore by condition: All Heart Failure With Preserved Ejection Fraction clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.