🏛️ Verified NIH Record • Updated 2026-06-05

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors (NCT04931342)

A Phase II, Open-Label, Multicenter, Platform Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Hoffmann-La Roche

🩺 Plain-English Summary (8th-Grade Level)

This study will evaluate the efficacy and safety of multiple biomarker-selected treatments in patients with persistent or recurrent rare epithelial ovarian, fallopian tube, or primary peritoneal tumors. Enrollment will take place in two phases: a preliminary phase followed by a potential expansion phase.

Who can join: Review the eligibility criteria below.

Location: UCSF Helen Diller Family CCC — San Francisco, California

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (41 Sites)

Showing the first 25 of 41 sites.

  • UCSF Helen Diller Family CCC — San Francisco, California
  • Washington University School of Medicine — St Louis, Missouri
  • Levine Cancer Institute — Charlotte, North Carolina
  • Ohio State University — Columbus, Ohio
  • University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma
  • Texas Oncology - Gulf Coast — The Woodlands, Texas
  • Virginia Oncology Associates — Norfolk, Virginia
  • University of Washington - Seattle Cancer Care Alliance — Seattle, Washington
  • Cabrini Hospital — Malvern, Victoria
  • Princess Margaret Cancer Center — Toronto, Ontario
  • McGill University Health Centre - Glen Site — Montreal, Quebec
  • Gynekologicko-porodnicka klinika — Prague,
  • CHU Besançon - Hôpital Jean Minjoz — Besançon,
  • Centre Francois Baclesse — Caen,
  • Centre Leon Berard — Lyon,
  • Groupe Hospitalier Diaconesses — Paris,
  • Centre Eugène Marquis — Rennes,
  • ICO - Site René Gauducheau — Saint-Herblain,
  • Institut Claudius Regaud — Toulouse,
  • Gustave Roussy — Villejuif,
  • Kliniken Essen-Mitte Evang. Huyssens-Stiftung, Klinik für Gynäkologie und gynäkologische Onkologie — Essen,
  • Universitätsklinikum Mannheim — Mannheim,
  • A.O. U. Consorziale Policlinico di Bari — Bari, Apulia
  • Istituto Tumori Napoli — Naples, Campania
  • Policlinico Universitario Agostino Gemelli — Rome, Lazio

📞 Contact the Study Coordinator

Phone: (877) 827-3222

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Ovarian Cancer clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗