🏛️ Verified NIH Record • Updated 2022-07-18
Efficacy and Safety Trial of PTP-001 (MOTYS) for Symptomatic Knee Osteoarthritis (NCT05100225)
A Multiple Arm, Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm, Phase 2 Study of Intra-Articular Administration of an Allogeneic Human Placental Tissue Particulate (PTP-001) for the Treatment of Knee Osteoarthritis
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Bioventus LLC
🩺 Plain-English Summary (8th-Grade Level)
Evaluation of safety, tolerability and efficacy of a single intra-articular (IA) injection of PTP-001, an allogeneic placental tissue particulate, in individuals with knee osteoarthritis (OA).
Who can join: Review the eligibility criteria below.
Location: Emeritus Research Sydney — Botany, New South Wales
Age range: 40 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (14 Sites)
- Emeritus Research Sydney — Botany, New South Wales
- Genesis Research Services — Broadmeadow, New South Wales
- Royal North Shore Hospital — Saint Leonards, New South Wales
- Holdsworth House Medical Practice — Sydney, New South Wales
- Emeritus Research Melbourne — Camberwell, Victoria
- Hamilton Medical Research Group — Hamilton, Ontario
- McMaster University Department of Surgery St. Joseph's Healthcare Hamilton — Hamilton, Ontario
- Canadian Phase Onward Inc. — Toronto, Ontario
- Diex Recherche Quebec Inc. — Québec, Quebec
- Centrede Recherche Saint-Louis — Québec, Quebec
- Diex Recherche Sherbrooke Inc. — Sherbrooke, Quebec
- Sanos Clinic Nordjylland — Gandrup,
- Sanos Clinic — Herlev,
- Sanos Clinic Syddanmark — Vejle,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Osteoarthritis, Knee
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- Genicular Radiofrequency Ablation Following Total Knee Arthroplasty — Calgary, Alberta
- Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis — Sacramento, California
- Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain — Tempe, Arizona
- Prospective Randomized Study of Cementless vs Cemented UKA — New Albany, Ohio
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Explore by condition: All Osteoarthritis, Knee clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.