๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-09

First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer (NCT05156866)

A Phase 1, First in Human, Dose-Escalation Study of TORL-2-307-ADC in Participants With Advanced Cancer

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: TORL Biotherapeutics, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-ADC in patients with advanced cancer

Who can join: Review the eligibility criteria below.

Location: Providence St. Jude Medical Center โ€” Fullerton, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (12 Sites)

  • Providence St. Jude Medical Center โ€” Fullerton, California
  • UCLA - JCCC Clinical Research Unit โ€” Los Angeles, California
  • Torrance Memorial Medical โ€” Torrance, California
  • Fort Wayne Medical Oncology and Hematology โ€” Fort Wayne, Indiana
  • Washington University School of Medicine-Siteman Cancer Center โ€” St Louis, Missouri
  • Texas Oncology-Austin โ€” Austin, Texas
  • Texas Oncology-Dallas โ€” Dallas, Texas
  • START San Antonio โ€” San Antonio, Texas
  • Texas Oncology-Tyler โ€” Tyler, Texas
  • Seoul National University Hospital โ€” Seoul,
  • Severance Hospital, Yonsei University Health System โ€” Seoul,
  • Seoul National University Bundang Hospital โ€” Seoul,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—