๐๏ธ Verified NIH Record โข Updated 2025-07-22
QTX3046 in Patients With KRAS G12D Mutations (NCT06428500)
A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of QTX3046 in Patients With Advanced Solid Tumors With KRAS G12D Mutations
๐ต Active, Not Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Quanta Therapeutics
๐ฉบ Plain-English Summary (8th-Grade Level)
Phase 1 study to determine the safety and tolerability of QTX3046 as a single agent or in combination with cetuximab.
Who can join: Review the eligibility criteria below.
Location: South Texas Accelerated Research Therapeutics, LLC Midwest โ Grand Rapids, Michigan
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (5 Sites)
- South Texas Accelerated Research Therapeutics, LLC Midwest โ Grand Rapids, Michigan
- Duke Cancer Center โ Durham, North Carolina
- The University of Texas MD Anderson Cancer Center โ Houston, Texas
- South Texas Accelerated Research Therapeutics, LLC San Antonio โ San Antonio, Texas
- Huntsman Cancer Institute, University of Utah โ Salt Lake City, Utah
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression โ Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors โ Glendale, California
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors โ Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer โ Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors โ San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.