๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-07-22

QTX3046 in Patients With KRAS G12D Mutations (NCT06428500)

A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of QTX3046 in Patients With Advanced Solid Tumors With KRAS G12D Mutations

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Quanta Therapeutics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Phase 1 study to determine the safety and tolerability of QTX3046 as a single agent or in combination with cetuximab.

Who can join: Review the eligibility criteria below.

Location: South Texas Accelerated Research Therapeutics, LLC Midwest โ€” Grand Rapids, Michigan

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • South Texas Accelerated Research Therapeutics, LLC Midwest โ€” Grand Rapids, Michigan
  • Duke Cancer Center โ€” Durham, North Carolina
  • The University of Texas MD Anderson Cancer Center โ€” Houston, Texas
  • South Texas Accelerated Research Therapeutics, LLC San Antonio โ€” San Antonio, Texas
  • Huntsman Cancer Institute, University of Utah โ€” Salt Lake City, Utah

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—