๐๏ธ Verified NIH Record โข Updated 2026-06-24
Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study (NCT05287451)
๐ข Recruiting Observational / Diagnostic ๐ Clinical Research Protocol Sponsor: M.D. Anderson Cancer Center
๐ฉบ Plain-English Summary (8th-Grade Level)
This is a prospective preference study that will evaluate non-inferiority of the innovative treatment (RRS with delayed RRO) as compared to the standard treatment (RRSO) with respect to high grade serous (ovarian) cancer incidence
Who can join: Review the eligibility criteria below.
Location: Dana Farber Cancer Institute โ Boston, Massachusetts
Age range: 18 Years
๐งช Interventions in This Study
- RIsk-Reducing Salpingectomy (RRS) (OTHER)
- Risk-Reducing Oophorectomy-RRO (OTHER)
- Risk-Reducing Salpingo-Oophorectomy-RRSO (OTHER)
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (9 Sites)
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Mayo Clinic โ Rochester, Minnesota
- WU St Louis โ St Louis, Missouri
- Mount Sinai Health System โ New York, New York
- Memorial Sloan Kettering Cancer Center โ New York, New York
- University of Pennsylvania โ Philadelphia, Pennsylvania
- Lyndon Baines Johnson General โ Houston, Texas
- M D Anderson Cancer Center โ Houston, Texas
- University of Washington โ Seattle, Washington
๐ Contact the Study Coordinator
Phone: (713) 822-4502
Email: rnitecki@mdanderson.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ovarian Cancer
- Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy โ New York, New York
- Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer โ Pittsburgh, Pennsylvania
- Trial on Radical Upfront Surgery in Advanced Ovarian Cancer โ New York, New York
- Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) โ Duarte, California
- Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302) โ Little Rock, Arkansas
- NeoVax With Nivolumab in Patients With Ovarian Cancer โ Boston, Massachusetts
Explore by condition: All Ovarian Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.