๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-10-27

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease (NCT05361382)

Longitudinal Multicenter Head-to-Head Harmonization of Tau PET Tracers

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Tharick Pascoal

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to compare/harmonize cross-sectional and longitudinal tau tangle measurements obtained with the tau PET radiopharmaceuticals Flortaucipir and MK-6240 to elucidate the advantages and caveats of their use in clinical trials/practice and provide parameters to integrate their estimates.

Who can join: Review the eligibility criteria below.

Location: Lawrence Berkeley National Laboratory โ€” Berkeley, California

Age range: 18 Years to 90 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (9 Sites)

  • Lawrence Berkeley National Laboratory โ€” Berkeley, California
  • University of California San Francisco โ€” San Francisco, California
  • Mayo Clinic โ€” Rochester, Minnesota
  • Washington University in St. Louis โ€” St Louis, Missouri
  • University of Pittsburgh โ€” Pittsburgh, Pennsylvania
  • Brown University โ€” Providence, Rhode Island
  • Houston Methodist Neurological Institute โ€” Houston, Texas
  • McGill University โ€” Montreal, Quebec
  • Sant Pau Biomedical Research Institute โ€” Barcelona, Spain

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—