๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-29

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer (NCT05445778)

Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRฮฑ-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AbbVie

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRฮฑ) expression.

Who can join: Review the eligibility criteria below.

Location: Usa Mitchell Cancer Institute /ID# 269661 โ€” Mobile, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (264 Sites)

Showing the first 25 of 264 sites.

  • Usa Mitchell Cancer Institute /ID# 269661 โ€” Mobile, Alabama
  • Honorhealth Virginia G. Piper Cancer Care Network - Biltmore /ID# 269987 โ€” Phoenix, Arizona
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 269573 โ€” Irvine, California
  • Moores Cancer Center at UC San Diego /ID# 269564 โ€” La Jolla, California
  • Kaiser Permanente - Los Angeles Medical Center /ID# 269541 โ€” Los Angeles, California
  • University Of California Irvine Medical Center /ID# 269572 โ€” Orange, California
  • Stanford Women'S Cancer Center /ID# 269552 โ€” Palo Alto, California
  • Kaiser Permanente - Riverside Medical Center /ID# 269539 โ€” Riverside, California
  • Kaiser Permanente Zion Medical Center /ID# 269537 โ€” San Diego, California
  • Kaiser Permanente - San Diego Medical Center /ID# 269540 โ€” San Diego, California
  • Kaiser Permanente - San Marcos Medical Offices /ID# 269542 โ€” San Marcos, California
  • Olive View-Ucla Medical Center /ID# 269584 โ€” Sylmar, California
  • John Muir Health - Walnut Creek Medical Center /ID# 269575 โ€” Walnut Creek, California
  • Broward General Medical Center /ID# 269577 โ€” Fort Lauderdale, Florida
  • Regional Cancer Center /ID# 269558 โ€” Fort Myers, Florida
  • Baptist Md Anderson Cancer Center - Jacksonville - Palm Avenue /ID# 269560 โ€” Jacksonville, Florida
  • Mount Sinai Medical Center /ID# 269582 โ€” Miami, Florida
  • Sarasota Memorial Hospital /ID# 269526 โ€” Sarasota, Florida
  • Northside Hospital /ID# 269660 โ€” Atlanta, Georgia
  • Rush University Medical Center /ID# 269583 โ€” Chicago, Illinois
  • University of Chicago Medical Center /ID# 269546 โ€” Chicago, Illinois
  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 269110 โ€” Indianapolis, Indiana
  • St. Vincent Indianapolis Hospital /ID# 269107 โ€” Indianapolis, Indiana
  • University of Iowa /ID# 269566 โ€” Iowa City, Iowa
  • The University of Kansas Cancer Center - Westwood /ID# 269106 โ€” Westwood, Kansas

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Ovarian Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—