Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer (NCT05445778)
Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRฮฑ-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab
๐ฉบ Plain-English Summary (8th-Grade Level)
GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRฮฑ) expression.
Who can join: Review the eligibility criteria below.
Location: Usa Mitchell Cancer Institute /ID# 269661 โ Mobile, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (264 Sites)
Showing the first 25 of 264 sites.
- Usa Mitchell Cancer Institute /ID# 269661 โ Mobile, Alabama
- Honorhealth Virginia G. Piper Cancer Care Network - Biltmore /ID# 269987 โ Phoenix, Arizona
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 269573 โ Irvine, California
- Moores Cancer Center at UC San Diego /ID# 269564 โ La Jolla, California
- Kaiser Permanente - Los Angeles Medical Center /ID# 269541 โ Los Angeles, California
- University Of California Irvine Medical Center /ID# 269572 โ Orange, California
- Stanford Women'S Cancer Center /ID# 269552 โ Palo Alto, California
- Kaiser Permanente - Riverside Medical Center /ID# 269539 โ Riverside, California
- Kaiser Permanente Zion Medical Center /ID# 269537 โ San Diego, California
- Kaiser Permanente - San Diego Medical Center /ID# 269540 โ San Diego, California
- Kaiser Permanente - San Marcos Medical Offices /ID# 269542 โ San Marcos, California
- Olive View-Ucla Medical Center /ID# 269584 โ Sylmar, California
- John Muir Health - Walnut Creek Medical Center /ID# 269575 โ Walnut Creek, California
- Broward General Medical Center /ID# 269577 โ Fort Lauderdale, Florida
- Regional Cancer Center /ID# 269558 โ Fort Myers, Florida
- Baptist Md Anderson Cancer Center - Jacksonville - Palm Avenue /ID# 269560 โ Jacksonville, Florida
- Mount Sinai Medical Center /ID# 269582 โ Miami, Florida
- Sarasota Memorial Hospital /ID# 269526 โ Sarasota, Florida
- Northside Hospital /ID# 269660 โ Atlanta, Georgia
- Rush University Medical Center /ID# 269583 โ Chicago, Illinois
- University of Chicago Medical Center /ID# 269546 โ Chicago, Illinois
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 269110 โ Indianapolis, Indiana
- St. Vincent Indianapolis Hospital /ID# 269107 โ Indianapolis, Indiana
- University of Iowa /ID# 269566 โ Iowa City, Iowa
- The University of Kansas Cancer Center - Westwood /ID# 269106 โ Westwood, Kansas
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ovarian Cancer
- Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy โ New York, New York
- Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer โ Pittsburgh, Pennsylvania
- Trial on Radical Upfront Surgery in Advanced Ovarian Cancer โ New York, New York
- Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) โ Duarte, California
- Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302) โ Little Rock, Arkansas
- NeoVax With Nivolumab in Patients With Ovarian Cancer โ Boston, Massachusetts
Explore by condition: All Ovarian Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.