SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer (NCT05451004)
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer. A Phase III Randomized Controlled Trial
🩺 Plain-English Summary (8th-Grade Level)
This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?
Who can join: Review the eligibility criteria below.
Location: City of Hope Corona — Corona, California
Age range: 18 Years
🧪 Interventions in This Study
- Lymphatic Mapping with SPECT-CT (OTHER)
- Ipsilateral and Contralateral Neck (RADIATION)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (38 Sites)
Showing the first 25 of 38 sites.
- City of Hope Corona — Corona, California
- City of Hope Comprehensive Cancer Center — Duarte, California
- City of Hope at Irvine Lennar — Irvine, California
- UM Sylvester Comprehensive Cancer Center at Coral Gables — Coral Gables, Florida
- Baptist MD Anderson Cancer Center — Jacksonville, Florida
- University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami, Florida
- Moffitt Cancer Center-International Plaza — Tampa, Florida
- Moffitt Cancer Center - McKinley Campus — Tampa, Florida
- Moffitt Cancer Center — Tampa, Florida
- Emory University Hospital Midtown — Atlanta, Georgia
- Northwestern University — Chicago, Illinois
- Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois
- The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky
- University of Michigan Rogel Cancer Center — Ann Arbor, Michigan
- University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan
- Henry Ford Hospital — Detroit, Michigan
- MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri
- UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina
- MetroHealth Medical Center — Cleveland, Ohio
- Providence Portland Medical Center — Portland, Oregon
- UT MD Anderson - The Woodlands — Conroe, Texas
- UT MD Anderson Cancer Center — Houston, Texas
- UT MD Anderson - West Houston — Houston, Texas
- UT MD Anderson - League City — League City, Texas
- UT MD Anderson - Sugar Land — Sugar Land, Texas
📞 Contact the Study Coordinator
Phone: (613) 533-6430
Email: wparulekar@ctg.queensu.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Oropharyngeal Cancer
- A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC) — Basking Ridge, New Jersey
- De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma — Prince George, British Columbia
- Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer — Gold Coast, Queensland
- A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers — Bethesda, Maryland
- Men and Women Offering Understanding of Throat HPV — Baltimore, Maryland
- Depression and Adherence in Head and Neck Cancer — Houston, Texas
Explore by condition: All Oropharyngeal Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.