Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR (NCT05459233)
Valve Hemodynamic Optimization Based on Doppler-Echocardiography Versus Catheterization Measurements Following Valve-in-Valve TAVR: A Prospective Randomized Trial
🩺 Plain-English Summary (8th-Grade Level)
Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,
Who can join: Review the eligibility criteria below.
Location: University of California — San Francisco, California
Age range: 18 Years
🧪 Interventions in This Study
- Doppler-echocardiography (PROCEDURE)
- Invasive hemodynamic measurements (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- University of California — San Francisco, California
- South Broward Hospital Disctrict D/B/A Memorial Healthcare System — Hollywood, Florida
- William Beaumont Hospital — Royal Oak, Michigan
- Mayo Clinic — Rochester, Minnesota
- St-Joseph's Health INC — Syracuse, New York
- The Christ Hospital Health Network — Cincinnati, Ohio
- IUCPQ — Québec, Quebec
📞 Contact the Study Coordinator
Phone: (418) 656-8711
Email: josep.rodes@criucpq.ulaval.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.