Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction (NCT05464940)
Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction in Patients With Paroxysmal Atrial Fibrillation: The COFFEE-AF Trial
🩺 Plain-English Summary (8th-Grade Level)
This "How caffeine Induces Atrial Tachyarrhythmias" trial will be a multi-center, randomized, double-blinded trial of intravenous caffeine versus placebo among patients undergoing pulmonary vein isolation procedures for Atrial Fibrillation(AF).
Who can join: Review the eligibility criteria below.
Location: Loma Linda University — Loma Linda, California
Age range: 21 Years to 90 Years
🧪 Interventions in This Study
- Intravenous caffeine (OTHER)
- Masked Placebo (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Loma Linda University — Loma Linda, California
- Menorah Medical Center — Overland Park, Kansas
- Kansas City Heart Rhythm Institute — Overland Park, Kansas
- Overland Park Regional Medical Center — Overland Park, Kansas
- Centerpoint Medical Center Clinic — Independence, Missouri
- Centerpoint Medical Center — Independence, Missouri
- Research Medical Center Clinic — Kansas City, Missouri
- Research Medical Center — Kansas City, Missouri
- Texas Cardiac Arrythmia Institute — Austin, Texas
📞 Contact the Study Coordinator
Phone: (816) 651-1969
Email: datkins@kchrf.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atrial Fibrillation
- CHAMPION-AF Clinical Trial — Birmingham, Alabama
- Reversal of Atrial Substrate to Prevent Atrial — Calgary, Alberta
- Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients — Rochester, New York
- REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry — Chandler, Arizona
- Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF) — Cleveland, Ohio
- Liraglutide Effect in Atrial Fibrillation — Miami, Florida
Explore by condition: All Atrial Fibrillation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.