๐๏ธ Verified NIH Record โข Updated 2026-03-23
Study of AV-1959D, an Amyloid Beta Vaccine (NCT05642429)
A Phase I, Randomized, Double-Blind Study to Evaluate Safety and Tolerability of Amyloid-ฮฒ Vaccine, AV-1959D, in Patients With Early Alzheimer's Disease.
๐ต Active, Not Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Institute for Molecular Medicine
๐ฉบ Plain-English Summary (8th-Grade Level)
Phase 1 clinical trial of AV-1959 amyloid-ฮฒ vaccine for Alzheimer's disease (AD).
Who can join: Review the eligibility criteria below.
Location: Banner Alzheimer's Institute โ Phoenix, Arizona
Age range: 60 Years to 85 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (6 Sites)
- Banner Alzheimer's Institute โ Phoenix, Arizona
- Hoag Memorial Hospital โ Newport Beach, California
- University of South Florida โ Tampa, Florida
- Alzheimer's Research and Treatment Center โ Wellington, Florida
- Accel Research โ Decatur, Georgia
- Global Medical Institutes Princeton Medical Institute โ Princeton, New Jersey
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.